Recent studies have found a deleterious effect of age on a wide variety of measures of
functional connectivity, and some hints at a relationship between connectivity at rest and …

Alzheimer9s disease (AD) is characterized by two hallmark molecular pathologies: amyloid
aβ 1–42 and Tau neurofibrillary tangles. To date, studies of functional connectivity MRI …

Late-life depression (LLD) is a particularly debilitating illness. Older adults suffering from
depression commonly experience poor outcomes in response to antidepressant treatments …

Aging is a physiological process accompanied by cognitive decline, principally in memory
and executive functions. Alterations in the connectivity of the default mode network (DMN) …

Healthy aging is associated with weaker functional connectivity within resting state brain
networks and stronger functional interaction between these networks. This phenomenon has …

A mechanistic understanding of the pathology of psychiatric disorders has been hampered
by extensive heterogeneity in biology, symptoms, and behavior within diagnostic categories …

Emerging studies have reported that functional brain networks change with increasing age.
Graph theory is applied to understand the age-related differences in brain behavior and …

Growing evidence suggests that healthy aging affects the configuration of large-scale
functional brain networks. This includes reducing network modularity and local efficiency …

Aging is associated with changes in brain structure and function with some brain regions
showing more age-related deterioration than others. There is evidence that regional …

The effects of age and gender on large-scale resting-state networks (RSNs) reflecting within-
and between-network connectivity in the healthy brain remain unclear. This study …