▪ Abstract Apoptosis, a physiological process for killing cells, is critical for the normal
development and function of multicellular organisms. Abnormalities in cell death control can …

Apoptosis is a morphologically distinct form of programmed cell death that plays a major role
during development, homeostasis, and in many diseases including cancer, acquired …

Deciphering how neuronal diversity is established and maintained requires a detailed
knowledge of neuronal gene expression throughout development. In contrast to mammalian …

The Hippo signaling pathway is widely considered a master regulator of organ growth
because of the prominent overgrowth phenotypes caused by experimental manipulation of …

The role of the cell-surface molecule CTLA-4 in the regulation of T cell activation has been
controversial. Here, lymph nodes and spleens of CTLA-4-deficient mice accumulated T cell …

Parkinson's disease is the second most common neurodegenerative disorder and is
characterized by the degeneration of dopaminergic neurons in the substantia nigra …

Among nonhuman primates, females often form strong bonds with kin and other group
members. These relationships are thought to have adaptive value for females, but direct …

Background: Size regulation is fundamental in developing multicellular organisms and
occurs through the control of cell number and cell size. Studies in Drosophila have identified …

Inorganic phosphate (Pi) is one of the essential molecules for life. However, little is known
about intracellular Pi metabolism and signalling in animal tissues. Following the observation …

We have isolated the" complete" repertoire of genes encoding the odorant receptors in
Drosophila and employ these genes to provide a molecular description of the organization …