Mitophagy in human diseases

L Doblado, C Lueck, C Rey, AK Samhan-Arias… - International journal of …, 2021 - mdpi.com
Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …

Eustress and distress: neither good nor bad, but rather the same?

J Bienertova‐Vasku, P Lenart, M Scheringer - BioEssays, 2020 - Wiley Online Library
The terms “eustress” and “distress” are widely used throughout the scientific literature. As of
February 2020, 203 items in the Web of Science show up in a search for “eustress,” …

Higher mortality in acute coronary syndrome patients without standard modifiable risk factors: results from a global meta-analysis of 1,285,722 patients

G Kong, YH Chin, B Chong, RSJ Goh, OZH Lim… - International Journal of …, 2023 - Elsevier
Background Standard modifiable cardiovascular risk factors (SMuRF), comprising diabetes,
hyperlipidemia, hypertension, and smoking, are used for risk stratification in acute coronary …

ST‐segment–elevation myocardial infarction (STEMI) patients without standard modifiable cardiovascular risk factors—how common are they, and what are their …

ST Vernon, S Coffey, M D'Souza, CK Chow… - Journal of the …, 2019 - Am Heart Assoc
Background Programs targeting the standard modifiable cardiovascular risk factors
(SMuRFs: hypertension, diabetes mellitus, hypercholesterolemia, smoking) are critical to …

Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures

S Sanada, I Komuro, M Kitakaze - American Journal of …, 2011 - journals.physiology.org
Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Role of apoptosis in cardiovascular disease

Y Lee, ÅB Gustafsson - Apoptosis, 2009 - Springer
Apoptosis plays a key role in the pathogenesis in a variety of cardiovascular diseases due to
loss of terminally differentiated cardiac myocytes. Cardiac myocytes undergoing apoptosis …

Current status of experimental animal skin flap models: ischemic preconditioning and molecular factors

JH Lee, HJ You, TY Lee, HJ Kang - International journal of molecular …, 2022 - mdpi.com
Skin flaps are necessary in plastic and reconstructive surgery for the removal of skin cancer,
wounds, and ulcers. A skin flap is a portion of skin with its own blood supply that is partially …

The role of Nrf2‐mediated pathway in cardiac remodeling and heart failure

S Zhou, W Sun, Z Zhang… - Oxidative medicine and …, 2014 - Wiley Online Library
Heart failure (HF) is frequently the consequence of sustained, abnormal neurohormonal,
and mechanical stress and remains a leading cause of death worldwide. The key …

LncRNA TUG1 mediates ischemic myocardial injury by targeting miR-132-3p/HDAC3 axis

Q Su, Y Liu, XW Lv, RX Dai… - American Journal of …, 2020 - journals.physiology.org
Increased production of reactive oxygen species (ROS) significantly contributed to the
pathogenesis of acute myocardial infarction (AMI). Recent studies suggest that hypoxia …

Protein kinase C and cardiac dysfunction: a review

RM Singh, E Cummings, C Pantos, J Singh - Heart failure reviews, 2017 - Springer
Heart failure (HF) is a physiological state in which cardiac output is insufficient to meet the
needs of the body. It is a clinical syndrome characterized by impaired ability of the left …