Prevalence and factors associated with polypharmacy: a systematic review and meta-analysis
Introduction Polypharmacy is commonly associated with adverse health outcomes. There
are currently no meta-analyses of the prevalence of polypharmacy or factors associated with …
are currently no meta-analyses of the prevalence of polypharmacy or factors associated with …
Association between use of antiepileptic drugs and fracture risk: a systematic review and meta-analysis
C Shen, F Chen, Y Zhang, Y Guo, M Ding - Bone, 2014 - Elsevier
Background It has been shown that antiepileptic drugs (AEDs) may have a detrimental effect
on bone health and translate into an increased risk of bone fracture. We aimed to …
on bone health and translate into an increased risk of bone fracture. We aimed to …
Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines
Background and objective Laboratories sometimes use different reference ranges for the
same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may …
same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may …
Costs of epilepsy and cost‐driving factors in children, adolescents, and their caregivers in G ermany
J Riechmann, A Strzelczyk, JP Reese, R Boor… - …, 2015 - Wiley Online Library
Objective To provide first data on the cost of epilepsy and cost‐driving factors in children,
adolescents, and their caregivers in Germany. Methods A population‐based, cross …
adolescents, and their caregivers in Germany. Methods A population‐based, cross …
Topiramate use early in pregnancy and the risk of oral clefts: a pregnancy cohort study
S Hernandez-Diaz, KF Huybrechts, RJ Desai… - Neurology, 2018 - AAN Enterprises
Objective To assess the relative risk of oral clefts associated with maternal use of high and
low doses of topiramate during the first trimester for epilepsy and nonepilepsy indications …
low doses of topiramate during the first trimester for epilepsy and nonepilepsy indications …
HLA‐A* 31: 01 and HLA‐B* 15: 02 as genetic markers for carbamazepine hypersensitivity in children
U Amstutz, CJD Ross… - Clinical …, 2013 - Wiley Online Library
The occurrence of hypersensitivity reactions including rare but life‐threatening Stevens–
Johnson syndrome (SJS) and drug‐induced hypersensitivity syndrome (HSS) limits the use …
Johnson syndrome (SJS) and drug‐induced hypersensitivity syndrome (HSS) limits the use …
How phenobarbital revolutionized epilepsy therapy: the story of phenobarbital therapy in epilepsy in the last 100 years
Z Yasiry, SD Shorvon - Epilepsia, 2012 - Wiley Online Library
Phenobarbital (phenobarbitone) was first used as an antiepileptic drug 100 years ago, in
1912. This article tells the story of the discovery of its antiepileptic action, its early …
1912. This article tells the story of the discovery of its antiepileptic action, its early …
Anti-seizure medications and quality of life in person with epilepsy
R Dwivedi, P Tiwari, M Pahuja, R Dada, M Tripathi - Heliyon, 2022 - cell.com
Objective The goal of this study was to determine the effects of mono-, bi-, and polytherapy
anti-seizure medications (ASMs) in terms of seizure reduction and quality of life (QOL) in …
anti-seizure medications (ASMs) in terms of seizure reduction and quality of life (QOL) in …
Dosing strategies for antiepileptic drugs: from a standard dose for all to individualised treatment by implementation of therapeutic drug monitoring
CJ Landmark, SI Johannessen, T Tomson - Epileptic Disorders, 2016 - Wiley Online Library
This review focuses on the evolution of approaches to dosing of antiepileptic drugs (AEDs)
in clinical practice through history. There has been a shift in the view of treatment of …
in clinical practice through history. There has been a shift in the view of treatment of …
Pharmacological aspects of antiseizure medications: From basic mechanisms to clinical considerations of drug interactions and use of therapeutic drug monitoring
Antiseizure medications (ASMs) are the cornerstone of treatment for patients with epilepsy.
Several new ASMs have recently been introduced to the market, making it possible to better …
Several new ASMs have recently been introduced to the market, making it possible to better …