Bioactivity of olive oil phenols in neuroprotection

C Angeloni, M Malaguti, MC Barbalace… - International Journal of …, 2017 - mdpi.com
Neurological disorders such as stroke, Alzheimer's and Parkinson's diseases are associated
with high morbidity and mortality, and few or no effective options are available for their …

Addressing the inter‐individual variation in response to consumption of plant food bioactives: towards a better understanding of their role in healthy aging and …

C Manach, D Milenkovic, T Van de Wiele… - Molecular nutrition & …, 2017 - Wiley Online Library
Bioactive compounds in plant‐based foods have health properties that contribute to the
prevention of age‐related chronic diseases, particularly cardiometabolic disorders …

Healthspan Maintenance and Prevention of Parkinson's-like Phenotypes with Hydroxytyrosol and Oleuropein Aglycone in C. elegans

G Brunetti, G Di Rosa, M Scuto, M Leri… - International journal of …, 2020 - mdpi.com
Numerous studies highlighted the beneficial effects of the Mediterranean diet (MD) in
maintaining health, especially during ageing. Even neurodegeneration, which is part of the …

[HTML][HTML] Novel insights into prebiotic properties on human health: A review

IA Neri-Numa, GM Pastore - Food Research International, 2020 - Elsevier
Dietary prebiotics can be metabolized by different colonic microorganisms and release
several classes of metabolites, particularly SCFAs into the intestine lumen, influencing the …

[HTML][HTML] Epigenetic effects of healthy foods and lifestyle habits from the Southern European Atlantic Diet pattern: a narrative review

PM Lorenzo, AG Izquierdo, G Rodriguez-Carnero… - Advances in …, 2022 - Elsevier
Recent scientific evidence has shown the importance of diet and lifestyle habits for the
proper functioning of the human body. A balanced and healthy diet, physical activity, and …

Effect of olive oil phenolic compounds on the expression of blood pressure-related genes in healthy individuals

S Martín-Peláez, O Castañer, V Konstantinidou… - European Journal of …, 2017 - Springer
Purpose To investigate whether the ingestion of olive oil having different phenolic contents
influences the expression of blood pressure-related genes, involved in the renin …

Flavanol Consumption in Healthy Men Preserves Integrity of Immunological‐Endothelial Barrier Cell Functions: Nutri (epi) genomic Analysis

D Milenkovic, A Rodriguez‐Mateos… - Molecular nutrition & …, 2022 - Wiley Online Library
Scope While cocoa flavanol (CF) consumption improves cardiovascular risk biomarkers,
molecular mechanisms underlying their protective effects are not understood. Objective To …

(−)-Epicatechin metabolites promote vascular health through epigenetic reprogramming of endothelial-immune cell signaling and reversing systemic low-grade …

D Milenkovic, K Declerck, Y Guttman, Z Kerem… - Biochemical …, 2020 - Elsevier
Abstract Ingestion of (−)-epicatechin flavanols reverses endothelial dysfunction by
increasing flow mediated dilation and by reducing vascular inflammation and oxidative …

Olive leaf polyphenols attenuate the clinical course of experimental autoimmune encephalomyelitis and provide neuroprotection by reducing oxidative stress …

J Giacometti, T Grubić-Kezele - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Numerous evidences suggest that plant polyphenols may have therapeutic benefits in
regulating oxidative stress and providing neuroprotection in many neurodegenerative …

A systems biology network analysis of nutri (epi) genomic changes in endothelial cells exposed to epicatechin metabolites

D Milenkovic, WV Berghe, C Morand, S Claude… - Scientific reports, 2018 - nature.com
Although vasculo-protective effects of flavan-3-ols are widely accepted today, their impact on
endothelial cell functions and molecular mechanisms of action involved is not completely …