Principles of exercise prescription, and how they influence exercise-induced changes of transcription factors and other regulators of mitochondrial biogenesis

C Granata, NA Jamnick, DJ Bishop - Sports Medicine, 2018 - Springer
Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …

Effects of sprint interval training on VO2max and aerobic exercise performance: A systematic review and meta‐analysis

M Sloth, D Sloth, K Overgaard… - Scandinavian journal of …, 2013 - Wiley Online Library
Recently, several studies have examined whether low‐volume sprint interval training (SIT)
may improve aerobic and metabolic function. The objective of this study was to …

The role of SIRT3 in exercise and aging

L Zhou, R Pinho, Y Gu, Z Radak - Cells, 2022 - mdpi.com
The health benefits of regular exercise are well established. Nonetheless, the molecular
mechanism (s) responsible for exercise-induced health benefits remain a topic of debate …

Exercise and sirtuins: a way to mitochondrial health in skeletal muscle

K Vargas-Ortiz, V Pérez-Vázquez… - International journal of …, 2019 - mdpi.com
The sirtuins form a family of evolutionarily conserved nicotinamide adenine dinucleotide
(NAD)-dependent deacetylases. Seven sirtuins (SIRT1–SIRT7) have been described in …

Effect of High-intensity Interval Training and Accumulated Exercise on PGC-1α and SIRT3 Levels in the Skeletal Muscle of Rats and Bioinformatics Analysis

M Xiao, X Xu, J Lu - 2021 International Conference on …, 2021 - ieeexplore.ieee.org
High-intensity interval training is effective in the prevention and treatment of chronic
diseases, with short exercise time, good exercise compliance and easy to adhere to the …

Discordant skeletal muscle gene and protein responses to exercise

DJ Bishop, NJ Hoffman, DF Taylor, NJ Saner… - Trends in Biochemical …, 2023 - cell.com
The ability of skeletal muscle to adapt to repeated contractile stimuli is one of the most
intriguing aspects of physiology. The molecular bases underpinning these adaptations …

Coordination of mitochondrial biogenesis by PGC-1α in human skeletal muscle: A re-evaluation

H Islam, BA Edgett, BJ Gurd - Metabolism, 2018 - Elsevier
The transcriptional co-activator peroxisome proliferator-activated receptor gamma co-
activator-1 alpha (PGC-1α) is proposed to coordinate skeletal muscle mitochondrial …

Human skeletal muscle fiber type-specific responses to sprint interval and moderate-intensity continuous exercise: acute and training-induced changes

LE Skelly, JB Gillen, BP Frankish… - Journal of Applied …, 2021 - journals.physiology.org
There are limited and equivocal data regarding potential fiber type-specific differences in the
human skeletal muscle response to sprint interval training (SIT), including how this …

Looking beyond PGC-1α: emerging regulators of exercise-induced skeletal muscle mitochondrial biogenesis and their activation by dietary compounds

H Islam, DA Hood, BJ Gurd - Applied Physiology, Nutrition, and …, 2020 - cdnsciencepub.com
Despite its widespread acceptance as the “master regulator” of mitochondrial biogenesis (ie,
the expansion of the mitochondrial reticulum), peroxisome proliferator-activated receptor …

The effect of 12-week resistance exercise training on serum levels of cellular aging process parameters in elderly men

B Hooshmand-Moghadam, M Eskandari… - Experimental …, 2020 - Elsevier
Background Regular physical activity has a positive effect on the prevention of cellular
aging. The present study investigated the effect of 12-week resistance training (RT) on …