Chemical and biological sensing using hybridization chain reaction

EE Augspurger, M Rana, MV Yigit - ACS sensors, 2018 - ACS Publications
Since the advent of its theoretical discovery more than 30 years ago, DNA nanotechnology
has been used in a plethora of diverse applications in both the fundamental and applied …

Nucleic acids-based functional nanomaterials for bioimaging

MR Cui, F Gao, ZY Shu, SK Ren, D Zhu… - Journal of Analysis and …, 2021 - Springer
Nucleic acids-based functional nanomaterials in biological imaging have drawn more and
more attention in recent years. The rapid development of various nanomaterials provides …

Size-dependent modulation of graphene oxide–aptamer interactions for an amplified fluorescence-based detection of aflatoxin B 1 with a tunable dynamic range

JJ Zhang, Z Li, S Zhao, Y Lu - Analyst, 2016 - pubs.rsc.org
Aflatoxin B1 (AFB1) is a common toxin found in many foods. While AFB1 sensors have been
reported, few studies have shown amplified detection with tunable dynamic ranges. We …

[HTML][HTML] Universal sensor array for highly selective system identification using two-dimensional nanoparticles

MS Hizir, NM Robertson, M Balcioglu, E Alp… - Chemical …, 2017 - pubs.rsc.org
A typical lock-and-key sensing strategy, relying only on the most dominant interactions
between the probe and target, could be too limiting. In reality, the information received upon …

Complex thermodynamic behavior of single-stranded nucleic acid adsorption to graphene surfaces

SV Ranganathan, K Halvorsen, CA Myers… - Langmuir, 2016 - ACS Publications
In just over a decade since its discovery, research on graphene has exploded due to a
number of potential applications in electronics, materials, and medicine. In its water-soluble …

Label-free and sensitive assay for deoxyribonuclease I activity based on enzymatically-polymerized superlong poly (thymine)-hosted fluorescent copper nanoparticles

L Luo, F Xu, H Shi, X He, T Qing, Y Lei, J Tang, D He… - Talanta, 2017 - Elsevier
Abstract Deoxyribonuclease I (DNase I) is an important physiological indicator and
diagnostic biomarker, but traditional methods for assessing its activity are time-consuming …

An end-point method based on graphene oxide for RNase H analysis and inhibitors screening

C Zhao, J Fan, L Peng, L Zhao, C Tong, W Wang… - Biosensors and …, 2017 - Elsevier
As a highly conserved damage repair protein, RNase H can hydrolysis DNA-RNA
heteroduplex endonucleolytically and cleave RNA-DNA junctions as well. In this study, we …

Unlocked Nucleic Acids for miRNA detection using two dimensional nano-graphene oxide

NM Robertson, AE Toscano, VE LaMantia… - Biosensors and …, 2017 - Elsevier
In this study we have used Unlocked Nucleic Acids (UNAs) to discriminate a breast cancer
oncomiR from two other miRNAs in the same RNA family using two-dimensional graphene …

Discriminating a single nucleotide difference for enhanced miRNA detection using tunable graphene and oligonucleotide nanodevices

NM Robertson, M Salih Hizir, M Balcioglu, R Wang… - Langmuir, 2015 - ACS Publications
In this study we have reported our efforts to address some of the challenges in the detection
of miRNAs using water-soluble graphene oxide and DNA nanoassemblies. Purposefully …

Systematic investigation of two-dimensional DNA nanoassemblies for construction of a nonspecific sensor array

N Nandu, MS Hizir, MV Yigit - Langmuir, 2018 - ACS Publications
We have performed a systematic study to analyze the effect of ssDNA length, nucleobase
composition, and the type of two-dimensional nanoparticles (2D-nps) on the desorption …