[HTML][HTML] Missing data is poorly handled and reported in prediction model studies using machine learning: a literature review

SWJ Nijman, AM Leeuwenberg, I Beekers… - Journal of clinical …, 2022 - Elsevier
Objectives Missing data is a common problem during the development, evaluation, and
implementation of prediction models. Although machine learning (ML) methods are often …

Modelling for policy: the five principles of the Neglected Tropical Diseases Modelling Consortium

MR Behrend, MG Basáñez, JID Hamley… - PLoS neglected …, 2020 - journals.plos.org
The neglected tropical diseases (NTDs) thrive mainly among the poorest populations of the
world. The World Health Organization (WHO) has set ambitious targets for eliminating much …

Biomarkers of AKI progression after pediatric cardiac surgery

JH Greenberg, M Zappitelli, Y Jia… - Journal of the …, 2018 - journals.lww.com
Background As children progress to higher stages of AKI, the risk for adverse outcomes
dramatically increases. No reliable methods exist to predict AKI progression in hospitalized …

Methodological issues in randomized clinical trials for prodromal Alzheimer's and Parkinson's disease

CH Aquino - Frontiers in Neurology, 2021 - frontiersin.org
Alzheimer's disease (AD) and Parkinson's disease (PD) are the first and second most
common neurodegenerative disorders, respectively. Both are proteinopathies with …

Applications of prediction models

EW Steyerberg, EW Steyerberg - Clinical prediction models: a practical …, 2019 - Springer
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Evaluating modeling and validation strategies for tooth loss

J Krois, C Graetz, B Holtfreter… - Journal of dental …, 2019 - journals.sagepub.com
Prediction models learn patterns from available data (training) and are then validated on
new data (testing). Prediction modeling is increasingly common in dental research. We …

Antimicrobial prophylaxis for vesicoureteral reflux: which subgroups of children benefit the most?

B Zhao, A Ivanova, N Shaikh - Pediatric Nephrology, 2024 - Springer
Abstract Background While the Randomized Intervention for Children with Vesicoureteral
Reflux (RIVUR) trial found that long-term antimicrobial prophylaxis reduced the risk of …

Evaluating biomarkers for prognostic enrichment of clinical trials

KF Kerr, J Roth, K Zhu, H Thiessen-Philbrook… - Clinical …, 2017 - journals.sagepub.com
Background/Aims: A potential use of biomarkers is to assist in prognostic enrichment of
clinical trials, where only patients at relatively higher risk for an outcome of interest are …

An ontology-based documentation of data discovery and integration process in cancer outcomes research

H Zhang, Y Guo, M Prosperi, J Bian - BMC Medical Informatics and …, 2020 - Springer
Background To reduce cancer mortality and improve cancer outcomes, it is critical to
understand the various cancer risk factors (RFs) across different domains (eg, genetic …

[HTML][HTML] Methodological issues in current practice may lead to bias in the development of biomarker combinations for predicting acute kidney injury

A Meisner, KF Kerr, H Thiessen-Philbrook, SG Coca… - Kidney international, 2016 - Elsevier
Individual biomarkers of renal injury are only modestly predictive of acute kidney injury (AKI).
Using multiple biomarkers has the potential to improve predictive capacity. In this systematic …