New evidence on the management of Lewy body dementia

JP Taylor, IG McKeith, DJ Burn, BF Boeve… - The Lancet …, 2020 - thelancet.com
Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body
dementia, are common neurodegenerative conditions. Patients with Lewy body dementia …

A guide to medications inducing salivary gland dysfunction, xerostomia, and subjective sialorrhea: a systematic review sponsored by the world workshop on oral …

A Wolff, RK Joshi, J Ekström, D Aframian… - Drugs in R&d, 2017 - Springer
Background Medication-induced salivary gland dysfunction (MISGD), xerostomia (sensation
of oral dryness), and subjective sialorrhea cause significant morbidity and impair quality of …

Freezing of gait in Parkinson's disease: pathophysiology, risk factors and treatments

C Gao, J Liu, Y Tan, S Chen - Translational neurodegeneration, 2020 - Springer
Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …

Summary of the recommendations of the EFNS/MDS‐ES review on therapeutic management of P arkinson's disease

JJ Ferreira, R Katzenschlager… - European journal of …, 2013 - Wiley Online Library
Objective To summarize the 2010 EFNS/MDS‐ES evidence‐based treatment
recommendations for the management of P arkinson's disease (PD). This summary includes …

The role of executive function and attention in gait

G Yogev‐Seligmann, JM Hausdorff… - … : official journal of the …, 2008 - Wiley Online Library
Until recently, gait was generally viewed as a largely automated motor task, requiring
minimal higher‐level cognitive input. Increasing evidence, however, links alterations in …

Priorities in Parkinson's disease research

WG Meissner, M Frasier, T Gasser, CG Goetz… - Nature reviews Drug …, 2011 - nature.com
The loss of dopaminergic neurons in the substantia nigra pars compacta leads to the
characteristic motor symptoms of Parkinson's disease: bradykinesia, rigidity and resting …

Postural instability in patients with Parkinson's disease: Epidemiology, pathophysiology and management

SD Kim, NE Allen, CG Canning, VSC Fung - CNS drugs, 2013 - Springer
Postural instability is one of the cardinal signs in Parkinson's disease (PD). It can be present
even at diagnosis, but becomes more prevalent and worsens with disease progression. It …

The interplay between gait, falls and cognition: can cognitive therapy reduce fall risk?

O Segev-Jacubovski, T Herman… - Expert review of …, 2011 - Taylor & Francis
In this article, we briefly summarize the incidence and significant consequences of falls
among older adults, the insufficient effectiveness of commonly used multifactorial …

Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa

Y Smith, T Wichmann, SA Factor… - …, 2012 - nature.com
The demonstration that dopamine loss is the key pathological feature of Parkinson's disease
(PD), and the subsequent introduction of levodopa have revolutionalized the field of PD …

A pathophysiological model of freezing of gait in Parkinson's disease

SJG Lewis, RA Barker - Parkinsonism & related disorders, 2009 - Elsevier
Freezing of gait (FOG) is a common phenomenon in Parkinson's disease (PD) affecting over
half of those in the advanced stages of the disease and often does not respond to standard …