abstract NANOG is a transcription factor that is involved in the self-renewal of embryonic
stem cells (ES) and is a critical factor for the maintenance of the undifferentiated state of …

Abstract The Bone Morphogenetic Protein (BMP) signaling pathway has established roles in
early embryonic morphogenesis, particularly in the epiblast. More recently, however, it has …

Background Oocyte maturation and preimplantation embryo development are controlled by
array of genes that are post-transcriptionally regulated by microRNAs. With respect to this …

Preeclampsia is a pregnancy-specific disease of high prevalence characterized by the onset
of hypertension, among other maternal or fetal signs. Its etiopathogenesis remains elusive …

The NOTCH signaling pathway plays an important role in regulating various biological
processes, including lineage specification and apoptosis. Multiple components of the …

Spermatozoal transcripts expression levels could be used to assess fertility potential of a
male. The objective of the present study was to elucidate the predictive ability of the …

Corpus luteum regression is related to an increased generation of reactive oxygen species.
Although several studies indicate that PGF (2alpha) is involved in regression of the corpus …

In many cell types, epigenetic changes are partially regulated by the availability of
metabolites involved in the activity of chromatin-modifying enzymes. Even so, the …

The uterus has a remarkable ability of cycling remodeling throughout the reproductive life of
the female. Recent findings in the human and mouse indicate that adult stem/progenitor …

The TGF-beta-SMAD signaling pathway is involved in regulation of various aspects of
female reproduction. However, the intrinsic functional role of SMADs in early embryogenesis …