The metabolism of glucose and lipids is essential for energy production in the body, and
dysregulation of the metabolic pathways of these molecules is implicated in various acute …

Protein post-translational modification (PTM) is a covalent process that occurs in proteins
during or after translation through the addition or removal of one or more functional groups …

Designing an RNA-interacting molecule that displays high therapeutic efficacy while
retaining specificity within a broad concentration range remains a challenging task …

O-linked β-DN-acetylglucosamine (O-GlcNAc), as a posttranslational modification (PTM), is
a reversible reaction that attaches β-N-GlcNAc to Ser/Thr residues on specific proteins by O …

Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …

O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a dynamic post-translational
modification that regulates thousands of proteins and almost all cellular processes. Aberrant …

Heart failure (HF) is one of the major causes of death among diabetic patients. Although
studies have shown that curcumin analog C66 can remarkably relieve diabetes-associated …

N-Acetylglucosamine (GlcNAc), a fundamental amino sugar moiety, is essential for protein
glycosylation, glycolipid, GPI-anchor protein, and cell wall components. Uridine diphosphate …

Abstract O‐linked‐β‐N‐acetylglucosamine (O‐GlcNAcylation) is a distinctive
posttranslational protein modification involving the coordinated action of O‐GlcNAc …

Cardiac fibrosis is insidious, accelerating cardiovascular diseases, heart failure, and death.
With a notable lack of effective therapies, advances in both understanding and targeted …