Terpenoids' anti-cancer effects: Focus on autophagy

C El-Baba, A Baassiri, G Kiriako, B Dia, S Fadlallah… - Apoptosis, 2021 - Springer
Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …

Natural products for the prevention and treatment of kidney disease

DQ Chen, HH Hu, YN Wang, YL Feng, G Cao, YY Zhao - Phytomedicine, 2018 - Elsevier
Background Chronic kidney disease (CKD) is one of the common causes resulting in a high
morbidity and mortality. Renal fibrosis is the main pathological features of CKD. Natural …

Potential therapeutic compounds from traditional Chinese medicine targeting endoplasmic reticulum stress to alleviate rheumatoid arthritis

IRSR Dias, HH Lo, K Zhang, BYK Law, AA Nasim… - Pharmacological …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease which affects about
0.5–1% of people with symptoms that significantly impact a sufferer's lifestyle. The cells …

Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells

J Zhang, L Liu, J Wang, B Ren, L Zhang, W Li - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Astragalus membranaceus which was originally described
in the Shennong's Classic of Materia Medica, the earliest complete Pharmacopoeia of China …

Therapeutic potential of Rhizoma Alismatis: a review on ethnomedicinal application, phytochemistry, pharmacology, and toxicology

LL Zhang, W Xu, YL Xu, X Chen… - Annals of the New …, 2017 - Wiley Online Library
Rhizoma Alismatis (RA), the dried rhizome of Alisma orientale (Sam.) Juzep, is a common
traditional herbal medicine named Ze Xie in Chinese. RA is an important herbal component …

Pharmacological Properties and Molecular Targets of Alisol Triterpenoids from Alismatis Rhizoma

C Bailly - Biomedicines, 2022 - mdpi.com
More than 100 protostane triterpenoids have been isolated from the dried rhizomes of
Alisma species, designated Alismatis rhizoma (AR), commonly used in Asian traditional …

DNA damage response and repair in ovarian cancer: Potential targets for therapeutic strategies

M Mirza-Aghazadeh-Attari, C Ostadian, AA Saei… - DNA repair, 2019 - Elsevier
Ovarian cancer is among the most lethal gynecologic malignancies with a poor survival
prognosis. The current therapeutic strategies involve surgery and chemotherapy. Research …

[HTML][HTML] Targeting endoplasmic reticulum stress signaling in ovarian cancer therapy

T Yan, X Ma, L Guo, R Lu - Cancer biology & medicine, 2023 - ncbi.nlm.nih.gov
The endoplasmic reticulum (ER), an organelle present in various eukaryotic cells, is
responsible for intracellular protein synthesis, post-translational modification, and folding …

Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation

Q Meng, X Duan, C Wang, Z Liu, P Sun… - Acta Pharmacologica …, 2017 - nature.com
Abstract Alisol B 23-acetate (AB23A) is a natural triterpenoid isolated from the traditional
Chinese medicine rhizoma alismatis, which exhibits a number of pharmacological activities …

Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: design of a glucomannan coating material

Y Niu, Q Li, R Xie, S Liu, R Wang, P Xing, Y Shi… - Biomaterials, 2017 - Elsevier
The biomaterials-host interaction is a dynamic process in which macrophages play a vital
role of regulation. Depending on the biochemical signals they sense, these highly plastic …