[HTML][HTML] Cardiac glycosides as novel cancer therapeutic agents

RA Newman, P Yang, AD Pawlus… - Molecular …, 2008 - triggered.stanford.clockss.org
The class of steroid-like compounds designated cardiac glycosides includes well-known
drugs such as digoxin, digitoxin, and ouabain. Their continued efficacy in treatment of …

Anticancer steroids: linking natural and semi-synthetic compounds

JAR Salvador, JFS Carvalho, MAC Neves… - Natural product …, 2013 - pubs.rsc.org
Covering: up to 2012 Steroids, a widespread class of natural organic compounds occurring
in animals, plants and fungi, have shown great therapeutic value for a broad array of …

[图书][B] Medicinal plants of Asia and the Pacific

C Wiart - 2006 - taylorfrancis.com
Drawing on the author's extensive personal experience, Medicinal Plants of Asia and the
Pacific provides comprehensive coverage of the medicinal plants of the region. Describing …

Glycosides from medicinal plants as potential anticancer agents: emerging trends towards future drugs

H Khan, M Saeedi, SM Nabavi… - Current medicinal …, 2019 - ingentaconnect.com
Background: Cancer continues to be a global burden, despite the advancement of various
technological and pharmaceutical improvements over the past two decades. Methods for …

Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum

LJ Rashan, K Franke, MM Khine, G Kelter… - Journal of …, 2011 - Elsevier
AIM OF THE STUDY: For identification of the active constituents we investigated the
anticancer activity of cardenolides from Streptocaulon tomentosum Wight & …

Enantioselective total synthesis of (+)-digitoxigenin

M Honma, M Nakada - Tetrahedron letters, 2007 - Elsevier
An enantioselective total synthesis of (+)-digitoxigenin is described. This total synthesis is
accomplished in a convergent manner using two chiral fragments prepared via the catalytic …

Research on the efficient enantioselective total synthesis of useful bioactive polycyclic compounds

M Nakada - Bulletin of the Chemical Society of Japan, 2022 - academic.oup.com
Useful bioactive polycyclic natural products are important targets in academic research,
wherein their mechanisms of action and total syntheses are commonly investigated. In …

Gordonic Acid, a Polyketide Glycoside Derived from Bacterial Coculture of Streptomyces and Gordonia Species

HB Park, JS Park, SI Lee, B Shin, DC Oh… - Journal of Natural …, 2017 - ACS Publications
Despite numerous efforts to discover novel bioactive products from microorganisms,
previously reported compounds are repetitively reisolated. A new polyketide glycoside …

Non-classical cardenolides from Calotropis gigantea exhibit anticancer effect as HIF-1 inhibitors

Z Zheng, Z Zhou, Q Zhang, X Zhou, J Yang… - Bioorganic …, 2021 - Elsevier
Six new non-classical cardenolides (1–6), and seventeen known ones (7–23) were isolated
from Calotropis gigantea. All cardenolides showed inhibitory effect on hypoxia inducible …

Structurally diversified diterpenoids from Euphorbia dracunculoides

L Wang, YT Ma, QY Sun, XN Li, Y Yan, J Yang… - Tetrahedron, 2015 - Elsevier
Extensive phytochemical investigation of the aerial parts of Euphorbia dracunculoides led to
the isolation of 19 structurally diversified diterpenoids with five different carbon skeletons …