Some environmental contaminants interact with hormones and may exert adverse
consequences as a result of their actions as endocrine disrupting chemicals (EDCs) …

The aryl hydrocarbon receptor (or AhR) is a cytoplasmic receptor of pollutants. It translocates
into the nucleus upon binding to its ligands, and forms a heterodimer with ARNT (AhR …

The US Tox21 program has screened a library of approximately 10,000 (10K) environmental
chemicals and drugs in three independent runs for estrogen receptor alpha (ERα) agonist …

Even though high doses of organic pollutants are toxic, relatively low concentrations have
been reported to cause long-term alterations in functioning of individual organisms …

Dibutyl phthalate (di-n-butyl phthalate, DBP) is one of the most commonly used phthalate
esters. DBP is widely used as a plasticizer in a variety of household industries and …

Background—Aryl hydrocarbon receptor (AhR) is a transcription factor that belongs to the
basic helix-loop-helix PAS (Per-Arnt-Sim homology domain) family known to mediate the …

Gut microbiota-derived tryptophan metabolites such as indole derivatives are an integral
part of host metabolome that could mediate gut–brain communication and contribute to host …

Abstract Di-(2-ethylhexyl) phthalate (DEHP) is used as a plasticizer in various plastic
compounds, such as polyvinyl chloride (PVC), and products including baby toys, packaging …

Triclosan (TCS) is an antimicrobial agent that is used extensively in personal care and in
sanitizing products, such as soaps, toothpastes, and hair products. A number of studies have …

Apoptosis and autophagy are involved in neural development and in the response of the
nervous system to a variety of insults. Apoptosis is responsible for cell elimination, whereas …