Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Methods: UDS Version 3 was developed after years of coordination between the National
Institute on Aging-appointed Clinical Task Force (CTF), clinicians from∼ 30 ADCs, and the …

Persistent DNA double-strand breaks (DSBs) in neurons are an early pathological hallmark
of neurodegenerative diseases including Alzheimer's disease (AD), with the potential to …

Alzheimer's disease (AD) is the most common type of neurodegenerative disease. Its typical
pathology consists of extracellular amyloid-β (Aβ) plaques and intracellular tau …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that accounts for a
majority of dementia cases. AD is characterized by progressive neuronal death associated …

Multiple Sclerosis (MS) is traditionally considered an autoimmune-mediated demyelinating
disease, the pathoetiology of which is unknown. However, the key question remains whether …

Oligodendrocytes (OLs) are a major type of glial cells in the central nervous system that
generate multiple myelin sheaths to wrap axons. Myelin ensures fast and efficient …

Purpose To optimize and apply deep neural network based CEST (deepCEST) and
apparent exchange dependent‐relaxation (deepAREX) for imaging the mouse brain with …

Background Alzheimer's disease (AD) is a neurodegenerative brain pathology formed due
to piling up of amyloid proteins, development of plaques and disappearance of neurons …

Carriers of the APOE4 (apolipoprotein E ε4) variant of the APOE gene are subject to several
age‐related health risks, including Alzheimer's disease (AD). The deficient lipid and …