As the major naturally occurring alkaloid in pepper with a pungent taste, piperine is known
for its beneficial biological functions and therapeutic effects. In this work, the bioavailability …

Age-related neurological disorders (ANDs), including neurodegenerative diseases, are
multifactorial disorders whose risk increases with age. The main pathological hallmarks of …

Oxidative stress is usually associated with many neurodegenerative diseases. In this study,
the gas chromatography–mass spectrometry (GC–MS) analysis of cold-pressed oil (CPO) …

Alzheimer's disease (AD) is a common neurodegenerative disorder that mainly affects the
aged population and is characterized by the progressive loss of the hippocampal and …

The nutraceutical system of curcumin-piperine in 2-hydroxypropyl-β-cyclodextrin was
prepared by using the kneading technique. Interactions between the components of the …

Objectives This review focused on the concept of dementia in the Unani system of medicine
and comprehensive, updated information on Majoon Vaj about the phytochemistry …

Alzheimer's disease (AD), which largely affects the elderly, has become a global burden.
Patients with AD have both short-and long-term memory impairments. The neuronal loss in …

Black pepper (Piper nigrum L.) is a storehouse of numerous bioactive compounds, most
important being the alkaloid piperine. This metabolite has immense applications in both food …

Ethnopharmacological relevance In traditional system of medicine, Piper species, or its
components are widely used to treat many diseases including memory improvement. One of …

Abstract Sirtuin1 (Sirt1) is an unusual target for aging and aging-associated diseases.
During the screening for Sirt1 activators from natural compounds, piperlongumine (PL), one …