Multicomponent reactions of ethyl trifluoroacetoacetate with carbonyl and nucleophilic reagents as a promising tool for organic synthesis

SO Kushch, MV Goryaeva, YV Burgart… - Russian Chemical …, 2023 - Springer
The review is summarized and systematized the published data on the multicomponent
reactions of ethyl trifluoroacetoacetate, carbonyl compounds (aldehydes and ketones), and …

Efficient synthesis of novel biginelli and hantzsch products sourced from biorenewable furfurals using gluconic acid aqueous solution as the green organocatalyst

HN Anchan, P Naik C, NS Bhat, M Kumari, S Dutta - ACS omega, 2023 - ACS Publications
The Biginelli reaction provides 3, 4-dihydropyrimidin-2 (1 H)-ones (DHPMs), whereas the
Hantzsch reaction leads to 1, 4-dihydropyridines (DHPs) by the one-pot, multicomponent …

Antitubercular evaluation of dihydropyridine–triazole conjugates: design, synthesis, in vitro screening, SAR and in silico ADME predictions

AK Kushawaha, AK Jaiswal, J Gupta, S Katiyar… - RSC Medicinal …, 2024 - pubs.rsc.org
This study investigates the potential of click chemistry for the development of novel anti-
tuberculosis agents. A targeted library of 1, 4-dihydropyridine–1, 2, 3-triazole conjugates …

Divergent Reaction of Activated Pyridines with α,α-Difluorinated gem-Diols: Regioselective Synthesis of gem-Difluorinated Dihydropyridines and Dihydropyridones

K Patra, MK Reddy, S Mallik, M Baidya - Organic Letters, 2022 - ACS Publications
The nucleophilic reactivity of α, α-difluorinated gem-diols toward activated pyridinium salts
has been capitalized in a highly regioselective fashion, offering biologically relevant 1, 4 …

Crystallographic and computational investigations of structural properties in phenyl and methoxy‑phenyl substituted 1, 4 dihydropyridine derivatives

J Ethiraj, R Ajin, RK Sankaranarayanan, R Sekar… - Journal of Molecular …, 2022 - Elsevier
Single crystal preparation of two 1, 4-dihydropyridine (1, 4-DHP) derivative molecules,
namely,(i) 2, 6-dimethyl-4-phenyl-1, 4-dihydro-pyridine-3, 5-dicarboxylic acid diethyl ester …

Preparation, characterization, and application of supported phosphate acid on the UiO-66-NH2 as an efficient and bifunctional catalyst for the synthesis of acridines

Z Karami, MM Khodaei - Research on Chemical Intermediates, 2023 - Springer
Most metal–organic frameworks (MOFs) as heterogeneous catalytic systems limit their use in
the catalytic process due to a lack of active functional sites. In this study, the novel …

ИЗВЕСТИЯ АКАДЕМИИ НАУК. СЕРИЯ ХИМИЧЕСКАЯ

СО Кущ, МВ Горяева, ЯВ Бургарт… - ИЗВЕСТИЯ АКАДЕМИИ …, 2023 - elibrary.ru
Обобщены и систематизированы данные литературы по многокомпонентным
реакциям трифторацетоуксусного эфира с карбонильными (альдегидами или …

Application of Compounds with Anti‐Cardiac Fibrosis Activity: A Review

YQ Meng, X Cui, S Li, CH Jin - Chemistry & Biodiversity - Wiley Online Library
Coronary heart disease, hypertension, myocarditis, and valvular disease cause myocardial
fibrosis, leading to heart enlargement, heart failure, heart rate failure, arrhythmia, and …

Hekzahidrokinolin türevlerinin sentezi, sitotoksik özelliklerinin, ros oluşturma potansiyellerinin ve enflamasyon mediyatörleri üzerine etkilerinin ın vitro …

G Çetin - 2022 - acikbilim.yok.gov.tr
Bu çalışmada enflamatuvar mediyatörler üzerinde antienflamatuvar aktivite göstermesi
beklenen alkil 2, 6, 6-trimetil-4-(disübstitüe fenil)-5-okso-1, 4, 5, 6, 7, 8-hekzahidrokinolin-3 …

ИСПОЛЬЗОВАНИЕ МАКРОАНАЛИЗА ТКАНЕЙ ПОСЛЕ ИНФАРКТА МИОКАРДА

ГА АРСАХАНОВА - INTERNATIONAL JOURNAL, 2021 - elibrary.ru
Комплексом макрометрических (отдельное взвешивание частей сердца, их
Планиметрия, массометрически-планиметрическая кардиометрия), микрометрических …