Elastomeric biomaterials for tissue engineering

Q Chen, S Liang, GA Thouas - Progress in polymer science, 2013 - Elsevier
Biomaterials play a critical role in engineering of tissue constructs, working as an artificial
extracellular matrix to support regeneration. Because the elastic stretchability is a major …

Adipose‐derived stem cells in tissue regeneration: a review

P Zuk - International Scholarly Research Notices, 2013 - Wiley Online Library
In 2001, researchers at the University of California, Los Angeles, described the isolation of a
new population of adult stem cells from liposuctioned adipose tissue. These stem cells, now …

[HTML][HTML] Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat …

M Georgiou, JP Golding, AJ Loughlin, PJ Kingham… - Biomaterials, 2015 - Elsevier
Adipose-derived stem cells were isolated from rats and differentiated to a Schwann cell-like
phenotype in vitro. The differentiated cells (dADSCs) underwent self-alignment in a tethered …

Stimulating the neurotrophic and angiogenic properties of human adipose-derived stem cells enhances nerve repair

PJ Kingham, MK Kolar, LN Novikova… - Stem cells and …, 2014 - liebertpub.com
In future, adipose-derived stem cells (ASC) might be used to treat neurological disorders. In
this study, the neurotrophic and angiogenic properties of human ASC were evaluated, and …

Biomaterials in co-culture systems: towards optimizing tissue integration and cell signaling within scaffolds

KG Battiston, JWC Cheung, D Jain, JP Santerre - Biomaterials, 2014 - Elsevier
Most natural tissues consist of multi-cellular systems made up of two or more cell types.
However, some of these tissues may not regenerate themselves following tissue injury or …

Self-assembled tetrahedral DNA nanostructures promote neural stem cell proliferation and neuronal differentiation

W Ma, X Shao, D Zhao, Q Li, M Liu, T Zhou… - … applied materials & …, 2018 - ACS Publications
Stem cell-based therapy is considered a promising approach for the repair of nervous
tissues. Neural stem cells (NSCs) cannot proliferate or differentiate efficiently; hence …

Intracerebral transplantation of adipose-derived mesenchymal stem cells alternatively activates microglia and ameliorates neuropathological deficits in Alzheimer's …

T Ma, K Gong, Q Ao, Y Yan, B Song… - Cell …, 2013 - journals.sagepub.com
Recent studies suggest that transplantation of mesenchymal stem cells might have
therapeutic effects in preventing pathogenesis of several neurodegenerative disorders …

Effect of platelet‐rich plasma (PRP) concentration on proliferation, neurotrophic function and migration of Schwann cells in vitro

C Zheng, Q Zhu, X Liu, X Huang, C He… - Journal of tissue …, 2016 - Wiley Online Library
Platelet‐rich plasma (PRP) contains various growth factors and appears to have the
potential to promote peripheral nerve regeneration, but evidence is lacking regarding its …

Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice

Y Yan, T Ma, K Gong, Q Ao, X Zhang… - Neural Regeneration …, 2014 - journals.lww.com
In the present study, we transplanted adipose-derived mesenchymal stem cells into the
hippocampi of APP/PS1 transgenic Alzheimer's disease model mice. Immunofluorescence …

The MMP-9/TIMP-1 axis controls the status of differentiation and function of myelin-forming Schwann cells in nerve regeneration

Y Kim, AG Remacle, AV Chernov, H Liu, I Shubayev… - PloS one, 2012 - journals.plos.org
Background Myelinating Schwann cells (mSCs) form myelin in the peripheral nervous
system. Because of the works by us and others, matrix metalloproteinase-9 (MMP-9) has …