Biophysics experiments performed at single-molecule resolution provide exceptional insight
into the structural details and dynamic behavior of biological systems. However, extracting …

Time-dependent single-molecule experiments contain rich kinetic information about the
functional dynamics of biomolecules. A key step in extracting this information is the …

Single-molecule and related experiments yield time series of an observable as it fluctuates
due to thermal motion. In such data, it can be difficult to distinguish fluctuating signal from …

The clustering of membrane-bound proteins facilitates their transport by cortical actin flow in
early Caenorhabditis elegans embryo cell polarity. PAR-3 clustering is critical for this …

This paper aims to provide a new perspective on understanding the resolution limit by
examining a recently proposed spectrum estimator based on the Christoffel-Darboux Kernel …

A preceding paper [M. Dhar, JA Dickinson, and MA Berg, J. Chem. Phys. 159, 054110
(2023)] shows how to remove additive noise from an experimental time series, allowing both …

What is resolution? A statistical minimax testing perspective on superresolution microscopy
Page 1 The Annals of Statistics 2021, Vol. 49, No. 4, 2292–2312 https://doi.org/10.1214/20-AOS2037 …

Organisms have evolved molecular clocks to track 24-hour day/night light cycles which
regulate all important physiological functions including metabolism, immunity, and cell-cycle …

Our work aims to solve some of the most significant and fundamental theoretical problems
involved in the current statistical modeling of stochastic processes in single-molecule …

The cell is a dense environment composes of proteins, nucleic acids, as well as other small
molecules, which are constantly bombarding each other and interacting. These interactions …