Diabetes, oxidative stress, and DNA damage modulate cranial neural crest cell development and the phenotype variability of craniofacial disorders
S Fitriasari, PA Trainor - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Craniofacial malformations are among the most common birth defects in humans and they
often have significant detrimental functional, aesthetic, and social consequences. To date …
often have significant detrimental functional, aesthetic, and social consequences. To date …
Epithelial to mesenchymal transition during mammalian neural crest cell delamination
R Zhao, PA Trainor - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Epithelial to mesenchymal transition (EMT) is a well-defined cellular process that was
discovered in chicken embryos and described as “epithelial to mesenchymal …
discovered in chicken embryos and described as “epithelial to mesenchymal …
Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development
KT Falcon, KEN Watt, S Dash, R Zhao… - Proceedings of the …, 2022 - National Acad Sciences
Ribosomal RNA (rRNA) transcription by RNA polymerase I (Pol I) is a critical rate-limiting
step in ribosome biogenesis, which is essential for cell survival. Despite its global function …
step in ribosome biogenesis, which is essential for cell survival. Despite its global function …
Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination
Epithelial to mesenchymal transition (EMT) is a cellular process that converts epithelial cells
to mesenchymal cells with migratory potential in developmental and pathological processes …
to mesenchymal cells with migratory potential in developmental and pathological processes …
AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development
E Van Otterloo, I Milanda, H Pike, JA Thompson, H Li… - Elife, 2022 - elifesciences.org
The facial surface ectoderm is essential for normal development of the underlying cranial
neural crest cell populations, providing signals that direct appropriate growth, patterning …
neural crest cell populations, providing signals that direct appropriate growth, patterning …
FSHD2-and BAMS-associated mutations confer opposing effects on SMCHD1 function
Structural maintenance of chromosomes flexible hinge domain-containing 1 (Smchd1) plays
important roles in epigenetic silencing and normal mammalian development. Recently …
important roles in epigenetic silencing and normal mammalian development. Recently …
Identification of an adverse outcome pathway (AOP) for chemical-induced craniofacial anomalies using the transgenic zebrafish model
S Liu, T Kawanishi, A Shimada, N Ikeda… - Toxicological …, 2023 - academic.oup.com
Craniofacial anomalies are one of the most frequent birth defects worldwide and are often
caused by genetic and environmental factors such as pharmaceuticals and chemical agents …
caused by genetic and environmental factors such as pharmaceuticals and chemical agents …
Transfer of nuclear and ribosomal material from Sox10-lineage cells to neurons in the mouse brain
F Mayrhofer, AM Hanson, MF Navedo… - Journal of Experimental …, 2023 - rupress.org
Material transfer is an essential form of intercellular communication to exchange information
and resources between cells. Material transfer between neurons and from glia to neurons …
and resources between cells. Material transfer between neurons and from glia to neurons …
Ift88 is involved in mandibular development
A Kitamura, M Kawasaki, K Kawasaki… - Journal of …, 2020 - Wiley Online Library
The mandible is a crucial organ in both clinical and biological fields due to the high
frequency of congenital anomalies and the significant morphological changes during …
frequency of congenital anomalies and the significant morphological changes during …
Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions
Metazoan development depends on tightly regulated gene expression programs that instruct
progenitor cells to adopt specialized fates. Recent work found that posttranslational …
progenitor cells to adopt specialized fates. Recent work found that posttranslational …