Since the publication of the 2018 European Society of Cardiology/European Society of
Hypertension (ESC/ESH) Guidelines for the Management of Arterial Hypertension, several …

Background Early studies suggest that radiofrequency-based renal denervation reduces
blood pressure in patients with moderate hypertension. We investigated whether an …

Recent randomized sham-controlled trials have demonstrated significant blood pressure
reductions following renal denervation (RDN) in patients with hypertension, both in the …

Renal denervation is a promising new non-pharmacological treatment for resistant
hypertension. However, there is a lack of data from Asian patients. The REQUIRE trial …

Background Resistant hypertension is highly prevalent among the general hypertensive
population and the clinical management of this condition remains problematic. Different …

Hypertension is a leading risk factor for cardiovascular morbidity and mortality. Despite the
widespread availability of both pharmacological and lifestyle therapeutic options, blood …

Catheter-based renal artery denervation (RAD) is entering a new era. After the disappointing
results of SYMPLICITY-HTN 3 trial in year 2014, several technical and methodological …

Resistant hypertension is defined as a lack of ambulatory blood pressure response to
optimized medical treatment after exclusion of secondary hypertension in patients who are …

The efficacy of renal denervation in the treatment of resistant hypertension has been
controversial, and new strategies for its therapy are urgently needed. We performed the …

Background Despite optimal medical therapy, a significant proportion of patients' blood
pressure remains uncontrolled. Catheter‐based renal denervation (RDN) has been …