Gap junctions comprise arrays of intercellular channels formed by connexin proteins and
provide for the direct communication between adjacent cells. This type of intercellular …

Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage
as defined by the UICC-TNM and American Joint Committee on Cancer classifications …

Glaucoma is one of the most common neurodegenerative diseases. Despite this, the earliest
stages of this complex disease are still unclear. This study was specifically designed to …

Glaucoma is a common ocular disorder that is a leading cause of blindness worldwide. It is
characterized by the dysfunction and loss of retinal ganglion cells (RGCs). Although many …

L1-CAM, a neuronal cell adhesion receptor, is also expressed in a variety of cancer cells.
Recent studies identified L1-CAM as a target gene of β-catenin-T-cell factor (TCF) signaling …

Trop-2 is a transmembrane signal transducer that can induce cancer growth. Using antibody
targeting and N-terminal Edman degradation, we show here that Trop-2 undergoes …

This article is the first to show that loss of connexin43 (Cx43) expression in colorectal tumors
is correlated with significantly shorter relapse‐free and overall survival. Cx43 was further …

Intestinal stem cells (ISC) are crucial players in colon epithelium physiology. The accurate
control of their auto-renewal, proliferation and differentiation capacities provides a constant …

Research towards biomarkers that predict patient outcome in colorectal cancer (CRC) is
rapidly expanding. However, none of these biomarkers have been recommended by the …

INTRODUCTION: Genomewide expression profiling has identified a number of genes
expressed at higher levels in synovial sarcoma than in other sarcomas. Our objectives in this …