Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …

Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

Achieving malaria elimination requires targeting the human reservoir of infection, including
those with asymptomatic infection. Smear-positive asymptomatic infections detectable by …

Male and female gametocytes are the components of the malaria parasite life cycle which
are taken up from an infected host bloodstream by mosquitoes and thus mediate disease …

Plasmodium falciparum gametocyte kinetics and infectivity may differ between chronic and
incident infections. In the current study, we assess parasite kinetics and infectivity to …

Infection with Plasmodium can elicit antibodies that inhibit parasite survival in the mosquito,
when they are ingested in an infectious blood meal. Here, we determine the transmission …

Background Artemisinin combination therapies (ACT), which are increasingly being
introduced for treatment of Plasmodium falciparum malaria, are more effective against …

Mass treatment as a means to reducing P. falciparum malaria transmission was used during
the first global malaria eradication campaign and is increasingly being considered for …