Cerebral blood flow (CBF) regulation is essential for normal brain function. The mammalian
brain has evolved a unique mechanism for CBF control known as neurovascular coupling …

Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

The measurement of vascular function in isolated vessels has revealed important insights
into the structural, functional, and biomechanical features of the normal and diseased …

Active neurons increase their energy supply by dilating nearby arterioles and capillaries.
This neurovascular coupling underlies blood oxygen level–dependent functional imaging …

Neuronal activity results in increased blood flow in the brain, a response named functional
hyperemia. Astrocytes play an important role in mediating this response. Neurotransmitters …

We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …

This article discusses retinal oxygenation and retinal metabolism by focusing on
measurements made with two of the principal methods used to study O 2 in the retina …

Highlights•The architecture of the cerebral vasculature sculpts the hemodynamics
response.•The BOLD signal is correlated with increases in gamma-band power in the LFP …

Dynamic adjustments to neuronal energy supply in response to synaptic activity are critical
for neuronal function. Glial cells known as astrocytes have processes that ensheath most …

The brain possesses two intricate mechanisms that fulfill its continuous metabolic needs:
cerebral autoregulation, which ensures constant cerebral blood flow over a wide range of …