Membranous nephropathy

P Ronco, L Beck, H Debiec, FC Fervenza… - Nature reviews Disease …, 2021 - nature.com
Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …

[HTML][HTML] Membranous nephropathy: integrating basic science into improved clinical management

DC Cattran, PE Brenchley - Kidney international, 2017 - Elsevier
Idiopathic membranous nephropathy (INM) remains a common cause of the nephrotic
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …

KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Rituximab or cyclophosphamide in the treatment of membranous nephropathy: the RI-CYCLO randomized trial

F Scolari, E Delbarba, D Santoro… - Journal of the …, 2021 - journals.lww.com
Background A cyclic corticosteroid-cyclophosphamide regimen is the first-line therapy for
membranous nephropathy. Compared with this regimen, rituximab therapy might have a …

[HTML][HTML] The STARMEN trial indicates that alternating treatment with corticosteroids and cyclophosphamide is superior to sequential treatment with tacrolimus and …

G Fernández-Juárez, J Rojas-Rivera, AE van De Logt… - Kidney international, 2021 - Elsevier
A cyclical corticosteroid-cyclophosphamide regimen is recommended for patients with
primary membranous nephropathy at high risk of progression. We hypothesized that …

Rituximab in idiopathic membranous nephropathy

P Ruggenenti, P Cravedi, A Chianca… - Journal of the …, 2012 - journals.lww.com
Selective depletion of B cells with the mAb rituximab may benefit the autoimmune
glomerular disease idiopathic membranous nephropathy (IMN). Here, we describe our …

The nephrotic syndrome

SR Orth, E Ritz - New England Journal of Medicine, 1998 - Mass Medical Soc
The nephrotic syndrome is defined by a urinary protein level exceeding 3.5 g per 1.73 m2 of
body-surface area per day. At the turn of the century, clinicians distinguished a nephritic …

[HTML][HTML] The KDIGO practice guideline on glomerulonephritis: reading between the (guide) lines—application to the individual patient

J Radhakrishnan, DC Cattran - Kidney international, 2012 - Elsevier
The KDIGO guideline for glomerulonephritis is designed to assist health-care providers in
treating patients with glomerular diseases. A guideline is not a set of rules but is intended to …

Rituximab therapy in idiopathic membranous nephropathy: a 2-year study

FC Fervenza, RS Abraham, SB Erickson… - Clinical journal of the …, 2010 - journals.lww.com
Background and objectives: It was postulated that in patients with membranous nephropathy
(MN), four weekly doses of Rituximab (RTX) would result in more effective B cell depletion, a …

[HTML][HTML] Cyclosporine in patients with steroid-resistant membranous nephropathy: a randomized trial

DC Cattran, GB Appel, LA Hebert, LG Hunsicker… - Kidney international, 2001 - Elsevier
Cyclosporine in patients with steroid-resistant membranous nephropathy: A randomized
trial. Background A clinical trial of cyclosporine in patients with steroid-resistant …