Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …

With the growing demand for next-generation health care, the integration of electronic
components into implantable medical devices (IMDs) has become a vital factor in achieving …

Insufficient intracellular anabolism is a crucial factor involved in many pathological
processes in the body,. The anabolism of intracellular substances requires the consumption …

Cutaneous wound healing, especially diabetic wound healing, is a common clinical
challenge. Reactive oxygen species (ROS) and bacterial infection are two major detrimental …

Electrostimulation has been recognized as a promising nonpharmacological treatment in
orthopedics to promote bone fracture healing. However, clinical applications have been …

Recently, strategies that can target the underlying mechanisms of phenotype change to
modulate the macrophage immune response from the standpoint of biological science have …

Chronic bioenergetic imbalances and inflammation caused by hyperglycemia are obstacles
that delay diabetic wound healing. However, it is difficult to directly deliver energy and …

Abstract Treatment of large bone defects represents a great challenge in orthopedic and
craniomaxillofacial surgery. Traditional strategies in bone tissue engineering have focused …

In clinical terms, bone grafting currently involves the application of autogenous, allogeneic,
or xenogeneic bone grafts, as well as natural or artificially synthesized materials, such as …

Bioenergy (ATP) is essentially required for supporting the osteogenic differentiation of bone
marrow mesenchymal stem cells (MSCs). However, factors such as high ROS levels and …