[HTML][HTML] Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

[HTML][HTML] Recent advances in the formulation of PLGA microparticles for controlled drug delivery

E Lagreca, V Onesto, C Di Natale, S La Manna… - Progress in …, 2020 - Springer
Polymeric microparticles (MPs) are recognized as very popular carriers to increase the
bioavailability and bio-distribution of both lipophilic and hydrophilic drugs. Among different …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

[HTML][HTML] Biomaterials in neurodegenerative disorders: a promising therapeutic approach

M Bordoni, E Scarian, F Rey, S Gagliardi… - International journal of …, 2020 - mdpi.com
Neurodegenerative disorders (ie, Alzheimer's disease, Parkinson's disease, amyotrophic
lateral sclerosis, and spinal cord injury) represent a great problem worldwide and are …

Chondroitin sulfate-based composites: a tour d'horizon of their biomedical applications

MAS Abourehab, S Baisakhiya, A Aggarwal… - Journal of Materials …, 2022 - pubs.rsc.org
Chondroitin sulfate (CS), a natural anionic mucopolysaccharide, belonging to the
glycosaminoglycan family, acts as the primary element of the extracellular matrix (ECM) of …

[HTML][HTML] Novel strategies for spinal cord regeneration

B Costăchescu, AG Niculescu, MG Dabija… - International Journal of …, 2022 - mdpi.com
A spinal cord injury (SCI) is one of the most devastating lesions, as it can damage the
continuity and conductivity of the central nervous system, resulting in complex …

[HTML][HTML] PLGA-based micro/nanoparticles: an Overview of their applications in respiratory diseases

X Guo, X Zuo, Z Zhou, Y Gu, H Zheng, X Wang… - International Journal of …, 2023 - mdpi.com
Respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD),
are critical areas of medical research, as millions of people are affected worldwide. In fact …

Collagen-based scaffolds: An auspicious tool to support repair, recovery, and regeneration post spinal cord injury

AT Mneimneh, MM Mehanna - International Journal of Pharmaceutics, 2021 - Elsevier
Spinal cord injury (SCI) is a perplexing traumatic disease that habitually gives ride to
permanent disability, motor, and sensory impairment. Despite the existence of several …

[HTML][HTML] Sustained delivery of chABC improves functional recovery after a spine injury

A Sharifi, A Zandieh, Z Behroozi, MR Hamblin… - BMC neuroscience, 2022 - Springer
Abstract Introduction Chondroitinase ABC (chABC) is an enzyme could improve
regeneration and thereby improving functional recovery of spinal cord injury (SCI) in rodent …

Extracellular matrix in neural plasticity and regeneration

YA Chelyshev, IM Kabdesh… - Cellular and molecular …, 2022 - Springer
The extracellular matrix (ECM) is a fundamental component of biological tissues. The ECM
in the central nervous system (CNS) is unique in both composition and function. Functions …