Multisystem physiological perspective of human frailty and its modulation by physical activity

JA Taylor, PL Greenhaff, DB Bartlett… - Physiological …, 2023 - journals.physiology.org
“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …

Aging, lifestyle and dementia

D Wahl, SM Solon-Biet, VC Cogger, L Fontana… - Neurobiology of …, 2019 - Elsevier
Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

Sedentary behavior and incident dementia among older adults

DA Raichlen, DH Aslan, MK Sayre, PK Bharadwaj… - Jama, 2023 - jamanetwork.com
Importance Sedentary behavior is associated with cardiometabolic disease and mortality,
but its association with dementia is unclear. Objective To investigate whether accelerometer …

[图书][B] Beyond multiple linear regression: applied generalized linear models and multilevel models in R

P Roback, J Legler - 2021 - taylorfrancis.com
Beyond Multiple Linear Regression: Applied Generalized Linear Models and Multilevel
Models in R is designed for undergraduate students who have successfully completed a …

Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK Biobank participants

SY Huang, YZ Li, YR Zhang, YY Huang, BS Wu… - Molecular …, 2022 - nature.com
Although sleep, physical activity and sedentary behavior have been found to be associated
with dementia risk, findings are inconsistent and their joint relationship remains unclear. This …

Leisure-time sedentary behaviors are differentially associated with all-cause dementia regardless of engagement in physical activity

DA Raichlen, YC Klimentidis… - Proceedings of the …, 2022 - National Acad Sciences
Sedentary behavior (SB) is associated with cardiometabolic disease and mortality, but its
association with dementia is currently unclear. This study investigates whether SB is …

Exercise dosage in reducing the risk of dementia development: Mode, duration, and intensity—A narrative review

S Wang, HY Liu, YC Cheng, CH Su - International journal of …, 2021 - mdpi.com
Senile dementia, also known as dementia, is the mental deterioration which is associated
with aging. It is characterized by a decrease in cognitive abilities, inability to concentrate …

Sedentary behaviours, cognitive function, and possible mechanisms in older adults: a systematic review

O Olanrewaju, S Stockwell, B Stubbs… - Aging clinical and …, 2020 - Springer
Background Physical activity can improve cognitive function of older adults, but the influence
of sedentary behaviour on cognition is less clear. This systematic review investigated …

Morning exercise mitigates the impact of prolonged sitting on cerebral blood flow in older adults

MJ Wheeler, DW Dunstan, B Smith… - Journal of applied …, 2019 - journals.physiology.org
Preventing declines in cerebral blood flow is important for maintaining optimal brain health
with aging. We compared the effects of a morning bout of moderate-intensity exercise, with …

Total sedentary time and cognitive function in middle-aged and older adults: A systematic review and meta-analysis

K Dillon, A Morava, H Prapavessis, L Grigsby-Duffy… - Sports Medicine …, 2022 - Springer
Background An estimated 47 million people have dementia globally, and around 10 million
new cases are diagnosed each year. Many lifestyle factors have been linked to cognitive …