SERS tags: novel optical nanoprobes for bioanalysis

Y Wang, B Yan, L Chen - Chemical reviews, 2013 - ACS Publications
Surface-enhanced Raman scattering (SERS) is an ultrasensitive vibrational spectroscopic
technique to detect molecules on or near the surface of plasmonic nanostructures, greatly …

Molecular imaging: current status and emerging strategies

MA Pysz, SS Gambhir, JK Willmann - Clinical radiology, 2010 - Elsevier
In vivo molecular imaging has a great potential to impact medicine by detecting diseases in
early stages (screening), identifying extent of disease, selecting disease-and patient-specific …

Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy

CL Zavaleta, BR Smith, I Walton… - Proceedings of the …, 2009 - National Acad Sciences
Raman spectroscopy is a newly developed, noninvasive preclinical imaging technique that
offers picomolar sensitivity and multiplexing capabilities to the field of molecular imaging. In …

Multifunctional nanoparticles–properties and prospects for their use in human medicine

N Sanvicens, MP Marco - Trends in biotechnology, 2008 - cell.com
A major aim of medicine has long been the early and accurate diagnosis of clinical
conditions, providing an efficient treatment without secondary effects. With the emergence of …

Single-molecule and single-nanoparticle SERS: from fundamental mechanisms to biomedical applications

XM Qian, SM Nie - Chemical Society Reviews, 2008 - pubs.rsc.org
This tutorial review discusses a new class of colloidal metal nanoparticles that is able to
enhance the efficiencies of surface-enhanced Raman scattering (SERS) by as much as …

Semiconductor quantum dots and metal nanoparticles: syntheses, optical properties, and biological applications

V Biju, T Itoh, A Anas, A Sujith, M Ishikawa - Analytical and bioanalytical …, 2008 - Springer
We review the syntheses, optical properties, and biological applications of cadmium
selenide (CdSe) and cadmium selenide–zinc sulfide (CdSe–ZnS) quantum dots (QDs) and …

SERS microscopy: nanoparticle probes and biomedical applications

S Schlücker - ChemPhysChem, 2009 - Wiley Online Library
Abstract Microspectroscopic imaging: Surface‐enhanced Raman scattering (SERS)
microscopy is a novel method of vibrational microspectroscopic imaging for the selective …

High-sensitivity nanosensors for biomarker detection

M Swierczewska, G Liu, S Lee, X Chen - Chemical Society Reviews, 2012 - pubs.rsc.org
High sensitivity nanosensors utilize optical, mechanical, electrical, and magnetic relaxation
properties to push detection limits of biomarkers below previously possible concentrations …

Surface-enhanced Raman scattering tags for rapid and homogeneous detection of circulating tumor cells in the presence of human whole blood

MY Sha, H Xu, MJ Natan, R Cromer - Journal of the American …, 2008 - ACS Publications
A novel, homogeneous SERS-based cell detection assay was developed for rapid and
direct enumeration of circulating tumor cells in the presence of whole blood. Magnetic beads …

Exploring the margins of SERS in practical domain: An emerging diagnostic modality for modern biomedical applications

MM Joseph, N Narayanan, JB Nair, V Karunakaran… - Biomaterials, 2018 - Elsevier
Excellent multiplexing capability, molecular specificity, high sensitivity and the potential of
resolving complex molecular level biological compositions augmented the diagnostic …