Bortezomib-based regimens for newly diagnosed multiple myeloma in China: a report of 12-year real-world data

J He, D He, X Han, G Zheng, G Wei, Y Zhao… - Frontiers in …, 2020 - frontiersin.org
Background: Improve the treatment quality might affect patients' efficacy and survival.
Methods: Five hundred thirty multiple myeloma patients treated in four hematological centers …

Daratumumab, cyclophosphamide, bortezomib, and dexamethasone for transplant-ineligible myeloma: AMaRC 03-16

P Mollee, J Reynolds, W Janowski, H Quach… - Blood …, 2024 - ashpublications.org
In newly diagnosed transplant-ineligible patients with myeloma, daratumumab has improved
outcomes when added to the standard-of-care regimens. In a randomized trial, we tested …

Efficacy and safety of once‐weekly versus twice‐weekly bortezomib in patients with hematologic malignancies: a meta‐analysis with trial sequential analysis

B Hu, Q Zhou, YY Hu, L Zhuang, L Yi… - … : The Journal of …, 2019 - Wiley Online Library
Study Objective To compare the efficacy and safety of once‐weekly and twice‐weekly
bortezomib therapy in patients with hematologic malignancies. Design Meta‐analysis of 13 …

Synergistic effects of bortezomib-OV therapy and anti-invasive strategies in glioblastoma: a mathematical model

Y Kim, J Lee, D Lee, HG Othmer - Cancers, 2019 - mdpi.com
It is well-known that the tumor microenvironment (TME) plays an important role in the
regulation of tumor growth and the efficacy of anti-tumor therapies. Recent studies have …

Dose intensity and treatment duration of bortezomib in transplant‐ineligible newly diagnosed multiple myeloma

G Ibarra, M Peña, L Abril, A Senín… - European Journal of …, 2021 - Wiley Online Library
Background Bortezomib‐related peripheral neuropathy (PN) affects a relevant proportion of
multiple myeloma (MM) patients treated with melphalan, prednisone, and bortezomib (VMP) …

Real-world Outcomes in Newly Diagnosed Multiple Myeloma Based on Interphase Fluorescent In situ Hybridization: A Retrospective Analysis

P Jain, P Jain, A Tikoo, T Singh, S Patkar… - Apollo …, 2024 - journals.sagepub.com
Introduction: Limited data exist on interphase fluorescent in situ hybridization (iFISH)-based
survival outcomes in newly diagnosed multiple myeloma (NDMM) from India. Objectives: To …

Receiving four or fewer cycles of therapy predicts poor survival in newly diagnosed transplant‐ineligible patients with myeloma who are treated with bortezomib …

S Boyle, C Wellard, EM Moore… - European Journal of …, 2021 - Wiley Online Library
Our study highlights that for patients with myeloma treated with the chemotherapy drug
bortezomib, the number of cycles of treatment received is an important predictor of survival …