Elucidating brain cell type specific gene expression patterns is critical towards a better
understanding of how cell-cell communications may influence brain functions and …

Cytokines are signaling proteins that were first characterized as components of the immune
response, but have been found to have pleiotropic effects in diverse aspects of body function …

Despite several decades of research on the nature and functional properties of neural stem
cells, which brought great advances in regenerative medicine, there is still a plethora of …

The emergent self-organization of a neuronal network in a developing nervous system is the
result of a remarkably orchestrated process involving a multitude of chemical, mechanical …

Induced pluripotent stem cell bear the potential to differentiate into any desired cell type and
hold large promise for disease-in-a-dish cell-modeling approaches. With the latest advances …

Mismatches between pre-clinical and clinical results of stem cell therapeutics for ischemic
stroke limit their clinical applicability. To overcome these discrepancies, precise planning of …

Human-derived neuronal cell lines are progressively being utilized in understanding
neurobiology and preclinical translational research as they are biologically more relevant …

Mammalian adult central nerve system (CNS) injuries are devastating because of the
intrinsic difficulties for effective neuronal regeneration. The greatest problem to be overcome …

Several neurotropic cytokines relay their signaling through the leukemia inhibitory factor
receptor. This 190 kDa subunit couples with the 130 kDa gp130 subunit to transduce …

Introduction Severe spinal cord injury often causes temporary or permanent damages in
strength, sensation, or autonomic functions below the site of the injury. So far, there is still no …