Pichia pastoris has been recognized as one of the most industrially important hosts for
heterologous protein production. Despite its high protein productivity, the optimization of P …

The rapid increase in the number of diabetic patients globally and exploration of alternate
insulin delivery methods such as inhalation or oral route that rely on higher doses, is bound …

Pichia pastoris, a methylotrophic yeast, is an established system for the production of
heterologous proteins, particularly biopharmaceuticals and industrial enzymes. To maximise …

The manufacture of recombinant therapeutics is a fastest-developing section of therapeutic
pharmaceuticals and presently plays a significant role in disease management. Yeasts are …

Bacterial inclusion bodies (IBs) are functional, non-toxic amyloids occurring in recombinant
bacteria showing analogies with secretory granules of the mammalian endocrine system …

The biopharmaceutical market is growing faster than ever, with two production systems
competing for market dominance: mammalian cells and microorganisms. In recent years …

The alcohol oxidase 1 promoter (P AOX1) of Pichia pastoris is commonly used for high level
expression of recombinant proteins. While the safety risk of methanol and tough process …

Developing affordable and easily manufactured SARS-CoV-2 vaccines will be essential to
achieve worldwide vaccine coverage and long-term control of the COVID-19 pandemic …

Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad
array of metabolic pathways employed for the production of primary and secondary …

Since the approval of recombinant insulin from Escherichia coli for its clinical use in the early
1980s, the amount of recombinant pharmaceutical proteins obtained by microbial …