PLA micro-and nano-particles

BK Lee, Y Yun, K Park - Advanced drug delivery reviews, 2016 - Elsevier
Poly (d, l-lactic acid)(PLA) has been widely used for various biomedical applications for its
biodegradable, biocompatible, and nontoxic properties. Various methods, such as emulsion …

Factors Relating to the Biodistribution & Clearance of Nanoparticles & Their Effects on In Vivo Application

Y Wei, L Quan, C Zhou, Q Zhan - Nanomedicine, 2018 - Taylor & Francis
Nanoparticles have promising biomedical applications for drug delivery, tumor imaging and
tumor treatment. Pharmacokinetics are important for the in vivo application of nanoparticles …

PLGA particles in immunotherapy

D Horvath, M Basler - Pharmaceutics, 2023 - mdpi.com
Poly (lactic-co-glycolic acid)(PLGA) particles are a widely used and extensively studied drug
delivery system. The favorable properties of PLGA such as good bioavailability, controlled …

Development and characterisation of HPMC films containing PLA nanoparticles loaded with green tea extract for food packaging applications

M Wrona, MJ Cran, C Nerín, SW Bigger - Carbohydrate polymers, 2017 - Elsevier
A novel active film material based on hydroxypropyl-methylcellulose (HPMC) containing
poly (lactic acid)(PLA) nanoparticles (NPs) loaded with antioxidant (AO) green tea extract …

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

J Costa-Gouveia, E Pancani, S Jouny, A Machelart… - Scientific reports, 2017 - nature.com
Tuberculosis (TB) is a leading infectious cause of death worldwide. The use of ethionamide
(ETH), a main second line anti-TB drug, is hampered by its severe side effects. Recently …

[HTML][HTML] Drug delivery systems for oral disease applications

Y Zhang, R Jiang, L Lei, Y Yang, T Hu - Journal of Applied Oral …, 2022 - SciELO Brasil
There are many restrictions on topical medications for the oral cavity. Various factors affect
the topical application of drugs in the oral cavity, an open and complex environment. The …

Cell penetrating peptide-modified poly (lactic-co-glycolic acid) nanoparticles with enhanced cell internalization

JM Steinbach, YE Seo, WM Saltzman - Acta biomaterialia, 2016 - Elsevier
The surface modification of nanoparticles (NPs) can enhance the intracellular delivery of
drugs, proteins, and genetic agents. Here we studied the effect of different surface ligands …

Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy

KD Srivastava, A Siefert, TM Fahmy, MJ Caplan… - Journal of Allergy and …, 2016 - Elsevier
Background Treatments to reverse peanut allergy remain elusive. Current clinical
approaches using peanut oral/sublingual immunotherapy are promising, but concerns about …

Effect of chitosan coating on PLGA nanoparticles for oral delivery of thymoquinone: In vitro, ex vivo, and cancer cell line assessments

S Alshehri, SS Imam, M Rizwanullah, KU Fakhri… - Coatings, 2020 - mdpi.com
In the present study, thymoquinone (TQ)-encapsulated chitosan-(CS)-coated poly (d, l-
lactide-co-glycolide)(PLGA) nanoparticles (NPs) were formulated using the emulsion …

Nanostructured liquid-crystalline particles for drug delivery

A Lancelot, T Sierra, JL Serrano - Expert Opinion on Drug Delivery, 2014 - Taylor & Francis
Introduction: Nanostructured lyotropic liquid crystal particles (LLC NPs) have proven to be
extremely useful tools for applications in drug delivery. These structured nanoparticles are …