Systemic inflammation associated with immune reconstitution inflammatory syndrome in persons living with HIV

CL Vinhaes, M Araujo-Pereira, R Tibúrcio… - Life, 2021 - mdpi.com
Antiretroviral therapy (ART) has represented a major advancement in the care of people
living with HIV (PLWHH), resulting in significant reductions in morbidity and mortality through …

Mechanisms and Cardiorenal Complications of Chronic Anemia in People with HIV

K Kamvuma, BM Hamooya, S Munsaka, SK Masenga… - Viruses, 2024 - mdpi.com
Chronic anemia is more prevalent in people living with HIV (PLWH) compared to the general
population. The mechanisms that drive chronic anemia in HIV are multifaceted and include …

Impact of persistent anemia on systemic inflammation and tuberculosis outcomes in persons living with HIV

FO Demitto, M Araújo-Pereira, CA Schmaltz… - Frontiers in …, 2020 - frontiersin.org
Tuberculosis (TB) is associated with systemic inflammation and anemia, which are
aggravated in persons living with HIV (PLWH). Here, we characterized the dynamics of …

Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the …

M Araújo-Pereira, S Krishnan, P Salgame… - …, 2023 - thelancet.com
Background Tuberculosis (TB) is an infectious morbidity that commonly occurs in people
living with HIV (PWH) and increases the progression of HIV disease, as well as the risk of …

Sex-related differences in inflammatory and immune activation markers before and after combined antiretroviral therapy initiation

JS Mathad, N Gupte, A Balagopal… - JAIDS Journal of …, 2016 - journals.lww.com
Background: Women progress to death at the same rate as men despite lower plasma HIV
RNA (viral load). We investigated sex-specific differences in immune activation and …

Development and validation of a prognostic nomogram for HIV/AIDS patients who underwent antiretroviral therapy: data from a China population-based cohort

X Hou, D Wang, J Zuo, J Li, T Wang, C Guo, F Peng… - …, 2019 - thelancet.com
Background Accurate forecast of the death risk is crucial to the administration of people
living with HIV/AIDS (PLHIV). We aimed to establish and validate an effective prognosis …

The burden of anemia among Chinese HIV-infected patients following the initiation of antiretroviral therapy in the treat-all era: a nationwide cohort study

L Wei, Y Zhao, X Gan, D Zhao, Y Wu, Z Dou… - BMC Infectious …, 2023 - Springer
Background To assess the prevalence of anemia before and after antiretroviral therapy
(ART) initiation and to identify impact of anemia on mortality among HIV-infected patients in …

Association between severe anaemia and inflammation, risk of IRIS and death in persons with HIV: a multinational cohort study

M Araújo-Pereira, V Sheikh, I Sereti… - …, 2022 - thelancet.com
Background After initiating antiretroviral therapy (ART), approximately 25% of people with
HIV (PWH) may develop Immune Reconstitution Inflammatory Syndrome (IRIS), which is …

Vitamin A and D deficiencies associated with incident tuberculosis in HIV-infected patients initiating antiretroviral therapy in multinational case-cohort study

MW Tenforde, A Yadav, DW Dowdy… - JAIDS Journal of …, 2017 - journals.lww.com
Methods: We conducted a case-cohort study (n= 332) within a randomized trial comparing 3
ART regimens in 1571 HIV treatment-naive adults from 9 countries. A subcohort of 30 …

Variation in C-reactive protein response according to host and mycobacterial characteristics in active tuberculosis

J Brown, K Clark, C Smith, J Hopwood, O Lynard… - BMC Infectious …, 2016 - Springer
Background The C-reactive protein (CRP) response is often measured in patients with active
tuberculosis (TB) yet little is known about its relationship to clinical features in TB, or whether …