Hidradenitis suppurativa

R Sabat, GBE Jemec, Ł Matusiak, AB Kimball… - Nature Reviews …, 2020 - nature.com
Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory
disorder, which affects the intertriginous skin and is associated with numerous systemic …

Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life

TV Nguyen, G Damiani, LAV Orenstein… - Journal of the …, 2021 - Wiley Online Library
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs
patients' quality of life. It is characterized by recurrent painful nodules, abscesses and …

Aetiology and pathogenesis of hidradenitis suppurativa

K Wolk, O Join‐Lambert, R Sabat - British Journal of …, 2020 - academic.oup.com
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder. Patients develop inflamed
nodules and abscesses and, at later stages of disease, epithelialized tunnels and scars in …

What causes hidradenitis suppurativa?—15 years after

CC Zouboulis, F Benhadou, AS Byrd… - Experimental …, 2020 - Wiley Online Library
The 14 authors of the first review article on hidradenitis suppurativa (HS) pathogenesis
published 2008 in EXPERIMENTAL DERMATOLOGY cumulating from the 1st International …

Sebaceous immunobiology-skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations

CC Zouboulis, T Coenye, L He, K Kabashima… - Frontiers in …, 2022 - frontiersin.org
This review presents several aspects of the innovative concept of sebaceous
immunobiology, which summarizes the numerous activities of the sebaceous gland …

[HTML][HTML] Immunopathogenesis of hidradenitis suppurativa and response to anti–TNF-α therapy

MM Lowe, HB Naik, S Clancy, M Pauli, KM Smith, Y Bi… - JCI insight, 2020 - ncbi.nlm.nih.gov
Hidradenitis suppurativa (HS) is a highly prevalent, morbid inflammatory skin disease with
limited treatment options. The major cell types and inflammatory pathways in skin of patients …

Epithelialized tunnels are a source of inflammation in hidradenitis suppurativa

K Navrazhina, JW Frew, P Gilleaudeau… - Journal of Allergy and …, 2021 - Elsevier
Background Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic,
painful, and burdensome inflammatory disease manifesting in nodules and abscesses, with …

Identification of biomarkers and critical evaluation of biomarker validation in hidradenitis suppurativa: a systematic review

S Der Sarkissian, S Hessam, JS Kirby… - JAMA …, 2022 - jamanetwork.com
Importance The identification and validation of biomarkers in hidradenitis suppurativa (HS)
has potential to improve the understanding and management of this chronic, burdensome …

Genetic variants associated with hidradenitis suppurativa

Q Sun, KA Broadaway, SN Edmiston… - JAMA …, 2023 - jamanetwork.com
Importance Hidradenitis suppurativa (HS) is a common and severely morbid chronic
inflammatory skin disease that is reported to be highly heritable. However, the genetic …

[HTML][HTML] Hidradenitis suppurativa is an autoinflammatory keratinization disease: a review of the clinical, histologic, and molecular evidence

JW Frew - JAAD international, 2020 - Elsevier
The pathogenic model of hidradenitis suppurativa is in the midst of a paradigm shift away
from a disorder of primary follicular occlusion to an autoinflammatory keratinization disease …