The extracellular microenvironment is a highly dynamic network of biophysical and
biochemical elements, which surrounds cells and transmits molecular signals. Extracellular …

Infantile hemangioma (IH) is the most prevalent benign vascular tumor in infants, with
distinct disease stages and durations. Despite the fact that the majority of IHs can regress …

Although stem cell-derived extracellular vesicles (EVs) have remarkable therapeutic
potential for various diseases, the therapeutic efficacy of EVs is limited due to their …

Implantable vascular devices are widely used in clinical treatments for various vascular
diseases. However, current approved clinical implantable vascular devices generally have …

Significant progress has been made in designing bone materials capable of directing
endogenous cells to promote vascularized bone regeneration. However, current strategies …

Cervical damage is the most prevalent type of spinal cord injury clinically, although few
preclinical research studies focus on this anatomical region of injury. Here we present a …

The production of small-diameter artificial vascular grafts continues to encounter numerous
challenges, with concerns regarding the degradation rate and endothelialization being …

Ischemic stroke is a devastating medical condition with poor prognosis due to the lack of
effective treatment modalities. Transplantation of human neural stem cells or primary neural …

Stimulating angiogenesis during wound healing continues to present a significant clinical
challenge, given the limitations of current strategies to maintain therapeutic doses of growth …

Integrins are heterodimers composed of α and β subunits that are bonded through non-
covalent interactions. Integrins mediate the dynamic connection between extracellular …