[HTML][HTML] Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers

S Nooraei, H Bahrulolum, ZS Hoseini… - Journal of …, 2021 - Springer
Virus-like particles (VLPs) are virus-derived structures made up of one or more different
molecules with the ability to self-assemble, mimicking the form and size of a virus particle but …

Production of virus-like particles for vaccines

J Fuenmayor, F Gòdia, L Cervera - New biotechnology, 2017 - Elsevier
Virus-like particles (VLPs) are nanostructures that resemble the structures of viruses. They
are composed of one or more structural proteins that can be arranged in several layers and …

[HTML][HTML] Construction of SARS-CoV-2 virus-like particles by mammalian expression system

R Xu, M Shi, J Li, P Song, N Li - Frontiers in bioengineering and …, 2020 - frontiersin.org
Virus-like particle (VLP) is a self-assembled nanostructure incorporating key viral structural
proteins. VLP resembles molecular and morphological features of authentic viruses but is …

[HTML][HTML] Interaction between virus-like particles (VLPs) and pattern recognition receptors (PRRs) from dendritic cells (DCs): toward better engineering of VLPs

J Zepeda-Cervantes, JO Ramírez-Jarquín… - Frontiers in …, 2020 - frontiersin.org
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …

Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …

Macropinocytosis: an endocytic pathway for internalising large gulps

JP Lim, PA Gleeson - Immunology and cell biology, 2011 - Wiley Online Library
Macropinocytosis is a regulated form of endocytosis that mediates the non‐selective uptake
of solute molecules, nutrients and antigens. It is an actin‐dependent process initiated from …

Traditional and new influenza vaccines

SS Wong, RJ Webby - Clinical microbiology reviews, 2013 - Am Soc Microbiol
The challenges in successful vaccination against influenza using conventional approaches
lie in their variable efficacy in different age populations, the antigenic variability of the …

Defining macropinocytosis

MC Kerr, RD Teasdale - Traffic, 2009 - Wiley Online Library
Macropinocytosis represents a distinct pathway of endocytosis in mammalian cells. This
actin‐driven endocytic process is not directly co‐ordinated by the presence of cargo but can …

Virus-like particles—universal molecular toolboxes

C Ludwig, R Wagner - Current opinion in biotechnology, 2007 - Elsevier
Virus-like particles (VLPs) are highly organised spheres that self-assemble from virus-
derived structural antigens. These stable and versatile subviral particles possess excellent …

[HTML][HTML] Novel platforms for the development of a universal influenza vaccine

A Kumar, TS Meldgaard, S Bertholet - Frontiers in immunology, 2018 - frontiersin.org
Despite advancements in immunotherapeutic approaches, influenza continues to cause
severe illness, particularly among immunocompromised individuals, young children, and …