Myelin is critical for healthy brain function. An accurate in vivo measure of myelin content
has important implications for understanding brain plasticity and neurodegenerative …

A first-ever spinal cord imaging meeting was sponsored by the International Spinal
Research Trust and the Wings for Life Foundation with the aim of identifying the current state …

Multiexponential T2 relaxation time measurement in the central nervous system shows a
component that originates from water trapped between the lipid bilayers of myelin. This …

Axon injury/loss, demyelination and inflammation are the primary pathologies in multiple
sclerosis lesions. Despite the prevailing notion that axon/neuron loss is the substrate of …

MRI relaxometry is sensitive to a variety of tissue characteristics in a complex manner, which
makes it both attractive and challenging for characterizing tissue. This article reviews the …

Myelin water imaging (MWI) is an MRI imaging biomarker for myelin. This method can
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …

Introduction We investigated brain demyelination in aging, mild cognitive impairment (MCI),
and dementia using a direct magnetic resonance imaging marker of myelin. Methods Brains …

Characterizing demyelination/degeneration of spinal pathways in traumatic spinal cord
injured (SCI) patients is crucial for assessing the prognosis of functional rehabilitation. Novel …

Myelin loss and iron accumulation are cardinal features of aging and various
neurodegenerative diseases. Oligodendrocytes incorporate iron as a metabolic substrate for …

In an age‐heterogeneous sample of healthy adults, we examined test–retest reliability (with
and without participant repositioning) of two popular MRI methods of estimating myelin …