Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?
R Bergquist, J Utzinger, J Keiser - Infectious diseases of poverty, 2017 - Springer
The current approach of morbidity control of schistosomiasis, a helminth disease of poverty
with considerable public health and socioeconomic impact, is based on preventive …
with considerable public health and socioeconomic impact, is based on preventive …
Chemotherapy for fighting schistosomiasis: past, present and future
P Mäder, GA Rennar, AMP Ventura… - …, 2018 - Wiley Online Library
Chemotherapy based on repeated doses of praziquantel remains the most effective control
strategy against schistosomiasis, a neglected tropical disease caused by platyhelminths of …
strategy against schistosomiasis, a neglected tropical disease caused by platyhelminths of …
Molecular modeling: Novel techniques in food and nutrition development
KR Surana, ED Ahire, VN Sonawane… - … Food Products and …, 2021 - taylorfrancis.com
Molecular modeling is central for understanding chemistry by providing improved tools for
investigating, interpreting, explaining, and discovering new phenomena. Molecular …
investigating, interpreting, explaining, and discovering new phenomena. Molecular …
[图书][B] Parasitology: an integrated approach
A Gunn, SJ Pitt - 2022 - books.google.com
Parasitology Highly detailed textbook on parasites and parasite relationships The fully
revised edition of Parasitology: An Integrated Approach holds true to its engaging and easy …
revised edition of Parasitology: An Integrated Approach holds true to its engaging and easy …
Discovery of new anti-schistosomal hits by integration of QSAR-based virtual screening and high content screening
Schistosomiasis is a debilitating neglected tropical disease, caused by flatworms of
Schistosoma genus. The treatment relies on a single drug, praziquantel (PZQ), making the …
Schistosoma genus. The treatment relies on a single drug, praziquantel (PZQ), making the …
Quinazolinone Azolyl Ethanols: Potential Lead Antimicrobial Agents with Dual Action Modes Targeting Methicillin-Resistant Staphylococcus Aureus DNA
XM Peng, LP Peng, S Li, SR Avula… - Future Medicinal …, 2016 - Taylor & Francis
Aim: Due to bacterial drug resistance, a new series of quinazolinone azolyl ethanols were
synthesized and evaluated. Results: In vitro antibacterial assay showed that triazolyl ethanol …
synthesized and evaluated. Results: In vitro antibacterial assay showed that triazolyl ethanol …
Discovery of novel antischistosomal agents by molecular modeling approaches
Schistosomiasis, a chronic neglected tropical disease caused by Schistosoma worms, is
reported in nearly 80 countries. Although the disease affects approximately 260 million …
reported in nearly 80 countries. Although the disease affects approximately 260 million …
The discovery of a novel series of compounds with single-dose efficacy against juvenile and adult Schistosoma species
JMF Gardner, NR Mansour, AS Bell… - PLoS neglected …, 2021 - journals.plos.org
Treatment and control of schistosomiasis depends on a single drug, praziquantel, but this is
not ideal for several reasons including lack of potency against the juvenile stage of the …
not ideal for several reasons including lack of potency against the juvenile stage of the …
[HTML][HTML] Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation
G Padalino, N El-Sakkary, LJ Liu, C Liu… - European Journal of …, 2021 - Elsevier
Schistosomiasis is a neglected disease of poverty that is caused by infection with blood fluke
species contained within the genus Schistosoma. For the last 40 years, control of …
species contained within the genus Schistosoma. For the last 40 years, control of …
Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box
S Biendl, C Häberli, J Keiser - Expert review of anti-infective …, 2022 - Taylor & Francis
Background Treatment and control of schistosomiasis rely on a single drug, praziquantel.
New orally active antischistosomals featuring novel molecular scaffolds are urgently needed …
New orally active antischistosomals featuring novel molecular scaffolds are urgently needed …