Metagenomics: application of genomics to uncultured microorganisms
J Handelsman - Microbiology and molecular biology reviews, 2004 - Am Soc Microbiol
Metagenomics (also referred to as environmental and community genomics) is the genomic
analysis of microorganisms by direct extraction and cloning of DNA from an assemblage of …
analysis of microorganisms by direct extraction and cloning of DNA from an assemblage of …
Review and re-analysis of domain-specific 16S primers
GC Baker, JJ Smith, DA Cowan - Journal of microbiological methods, 2003 - Elsevier
The Polymerase Chain Reaction (PCR) has facilitated the detection of unculturable
microorganisms in virtually any environmental source and has thus been used extensively in …
microorganisms in virtually any environmental source and has thus been used extensively in …
Sponge-associated microorganisms: evolution, ecology, and biotechnological potential
MW Taylor, R Radax, D Steger… - … and molecular biology …, 2007 - Am Soc Microbiol
Marine sponges often contain diverse and abundant microbial communities, including
bacteria, archaea, microalgae, and fungi. In some cases, these microbial associates …
bacteria, archaea, microalgae, and fungi. In some cases, these microbial associates …
The Sorcerer II Global Ocean Sampling Expedition: Northwest Atlantic through Eastern Tropical Pacific
The world's oceans contain a complex mixture of micro-organisms that are for the most part,
uncharacterized both genetically and biochemically. We report here a metagenomic study of …
uncharacterized both genetically and biochemically. We report here a metagenomic study of …
Metagenomics: genomic analysis of microbial communities
CS Riesenfeld, PD Schloss, J Handelsman - Annu. Rev. Genet., 2004 - annualreviews.org
▪ Abstract Uncultured microorganisms comprise the majority of the planet's biological
diversity. Microorganisms represent two of the three domains of life and contain vast …
diversity. Microorganisms represent two of the three domains of life and contain vast …
Exploring prokaryotic diversity in the genomic era
P Hugenholtz - Genome biology, 2002 - Springer
Our understanding of prokaryote biology from study of pure cultures and genome
sequencing has been limited by a pronounced sampling bias towards four bacterial phyla …
sequencing has been limited by a pronounced sampling bias towards four bacterial phyla …
The bacterial species definition in the genomic era
KT Konstantinidis, A Ramette… - … Transactions of the …, 2006 - royalsocietypublishing.org
The bacterial species definition, despite its eminent practical significance for identification,
diagnosis, quarantine and diversity surveys, remains a very difficult issue to advance …
diagnosis, quarantine and diversity surveys, remains a very difficult issue to advance …
Marine sponges as microbial fermenters
U Hentschel, KM Usher… - FEMS microbiology …, 2006 - academic.oup.com
The discovery of phylogenetically complex, yet highly sponge-specific microbial
communities in marine sponges, including novel lineages and even candidate phyla, came …
communities in marine sponges, including novel lineages and even candidate phyla, came …
Cleaning up with genomics: applying molecular biology to bioremediation
DR Lovley - Nature Reviews Microbiology, 2003 - nature.com
Bioremediation has the potential to restore contaminated environments inexpensively yet
effectively, but a lack of information about the factors controlling the growth and metabolism …
effectively, but a lack of information about the factors controlling the growth and metabolism …
[图书][B] Anticancer agents from natural products
GM Cragg, DGI Kingston, DJ Newman - 2005 - taylorfrancis.com
Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …
and signaling systems that are designed to protect them from predators and provide other …