Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration
Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …
spaceflight biology that guide our current understanding of fundamental molecular changes …
Biomonitoring and precision health in deep space supported by artificial intelligence
Human exploration of deep space will involve missions of substantial distance and duration.
To effectively mitigate health hazards, paradigm shifts in astronaut health systems are …
To effectively mitigate health hazards, paradigm shifts in astronaut health systems are …
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight
Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses
myriad biomedical challenges to the human body, which are becoming increasingly relevant …
myriad biomedical challenges to the human body, which are becoming increasingly relevant …
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight
As spaceflight becomes more common with commercial crews, blood-based measures of
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
crew health can guide both astronaut biomedicine and countermeasures. By profiling …
Biological research and self-driving labs in deep space supported by artificial intelligence
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …
organisms, develop foundational knowledge to support deep space exploration and …
[HTML][HTML] Routine omics collection is a golden opportunity for European human research in space and analog environments
Widespread generation and analysis of omics data have revolutionized molecular medicine
on Earth, yet its power to yield new mechanistic insights and improve occupational health …
on Earth, yet its power to yield new mechanistic insights and improve occupational health …
One digital health for more FAIRness
O Tamburis, A Benis - Methods of information in medicine, 2022 - thieme-connect.com
Background One Digital Health (ODH) aims to propose a framework that merges One
Health's and Digital Health's specific features into an innovative landscape. FAIR (Findable …
Health's and Digital Health's specific features into an innovative landscape. FAIR (Findable …
Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice
The adverse effects of microgravity exposure on mammalian physiology during spaceflight
necessitate a deep understanding of the underlying mechanisms to develop effective …
necessitate a deep understanding of the underlying mechanisms to develop effective …
NASA GeneLab RNA-seq consensus pipeline: standardized processing of short-read RNA-seq data
EG Overbey, AM Saravia-Butler, Z Zhang, KS Rathi… - Iscience, 2021 - cell.com
With the development of transcriptomic technologies, we are able to quantify precise
changes in gene expression profiles from astronauts and other organisms exposed to …
changes in gene expression profiles from astronauts and other organisms exposed to …