Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting
catalytic step in the melanin biosynthesis and enzymatic browning. As a promising target …

Natural water sources are very often contaminated by municipal wastewater discharges
which contain either of xenobiotic pollutants and their sometimes more toxic degradation …

Abstract Background Button mushroom (Agaricus bisporus) is widely used on the world
market. Browning of mushroom surface is the most intuitive factor affecting consumer …

In this study, the content, structure, antityrosinase activity, and mechanism of longan bark
condensed tannins were evaluated. The findings obtained from mass spectrometry …

A novel series of twenty-seven cinnamides constituted by cinnamic acid derivatives liked to
1-aryl piperazines were synthesized and evaluated for their potential inhibitory diphenolase …

Tyrosinase and its related proteins are responsible for pigmentation disorders, and inhibiting
tyrosinase is an established strategy to treat hyperpigmentation. The carbonyl scaffolds can …

Safety concerns are the primary consideration to identify and detection of enzyme inhibitors.
In this regard, safe and potent tyrosinase inhibitors play important role in enhancing …

Tyrosinase (TYR, EC 1.14. 18.1), a critical enzyme participating in melanogenesis, catalyzes
the first two steps in melanin biosynthesis including the ortho-hydroxylation of L-tyrosine and …

Abnormal melanogenesis results in excessive production of melanin, leading to
pigmentation disorders. As a key and rate-limiting enzyme for melanogenesis, tyrosinase …