During the last decades, lipids have gained much attention due to their involvement in
health and disease. Lipids are required for the formation of membranes and contribute to …

Due to its genetic tractability and increasing wealth of accessible data, the yeast
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …

Lipins are phosphatidate phosphatases that generate diacylglycerol (DAG). In this study, we
report that yeast lipin, Pah1p, controls the formation of cytosolic lipid droplets. Disruption of …

Lipids are essential components for life. Their various structural and physical properties
influence diverse cellular processes and, thereby, human health. Lipids are not genetically …

The endoplasmic reticulum (ER) is an interconnected network of tubular and planar
membranes that supports the synthesis and export of proteins, carbohydrates and lipids …

Lipid droplets (LDs) and peroxisomes are central players in cellular lipid homeostasis: some
of their main functions are to control the metabolic flux and availability of fatty acids (LDs and …

As eukaryotic cells progress through cell division, the nuclear envelope (NE) membrane
must expand to accommodate the formation of progeny nuclei. In Saccharomyces …

Mitochondrial membrane phospholipids are essential for the mitochondrial architecture, the
activity of respiratory proteins, and the transport of proteins into the mitochondria. The …

Maintenance of energy homeostasis depends on the highly regulated storage and release
of triacylglycerol primarily in adipose tissue, and excessive storage is a feature of common …

Storage of non-polar lipids in ubiquitous eukaryotic organelles, lipid droplets (LDs), prevents
the toxic consequences of unesterified fatty acids and provides a lipid reservoir that can be …