Risk stratification and early detection biomarkers for precision HCC screening

YT Lee, N Fujiwara, JD Yang, Y Hoshida - Hepatology, 2023 - journals.lww.com
Hepatocellular carcinoma (HCC) mortality remains high primarily due to late diagnosis as a
consequence of failed early detection. Professional societies recommend semi‐annual HCC …

Updating the clinical application of blood biomarkers and their algorithms in the diagnosis and surveillance of hepatocellular carcinoma: a critical review

E Shahini, G Pasculli, AG Solimando, C Tiribelli… - International Journal of …, 2023 - mdpi.com
The most common primary liver cancer is hepatocellular carcinoma (HCC), and its mortality
rate is increasing globally. The overall 5-year survival of patients with liver cancer is …

The performance of GALAD score for diagnosing hepatocellular carcinoma in patients with chronic liver diseases: a systematic review and meta-analysis

MC Guan, SY Zhang, Q Ding, N Li, TT Fu… - Journal of Clinical …, 2023 - mdpi.com
Background GALAD score, comprising five clinical parameters, is a predictive model
developed for hepatocellular carcinoma (HCC) detection. Since its emergence, its …

[PDF][PDF] Current and emerging tools for hepatocellular carcinoma surveillance

N Adeniji, R Dhanasekaran - Hepatology communications, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related mortality worldwide.
Early detection of HCC enables patients to avail curative therapies that can improve patient …

HCC biomarkers–state of the old and outlook to future promising biomarkers and their potential in everyday clinical practice

S Schlosser, D Tümen, B Volz, K Neumeyer… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the most common and deadly tumors worldwide.
Management of HCC depends on reliable biomarkers for screening, diagnosis, and …

Application of Machine Learning Techniques to Assess Alpha-Fetoprotein at Diagnosis of Hepatocellular Carcinoma

S Gil-Rojas, M Suárez, P Martínez-Blanco… - International Journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary liver tumor and is associated
with high mortality rates. Approximately 80% of cases occur in cirrhotic livers, posing a …

Decreasing trend of serum α-fetoprotein level in hepatocellular carcinoma

A Vipani, M Lauzon, M Luu, LR Roberts… - Clinical …, 2022 - cghjournal.org
Serum a-fetoprotein (AFP), a well-established biomarker for hepatocellular carcinoma
(HCC), increases the sensitivity of ultrasound-based surveillance programs for early stage …

[HTML][HTML] Hepatocellular carcinoma risk scores for non-viral liver disease: A systematic review and meta-analysis

L Burke, A Hinkson, V Haghnejad, R Jones, R Parker… - JHEP Reports, 2024 - Elsevier
Background Hepatocellular carcinoma (HCC) risk prediction models may provide a more
personalised approach to surveillance for HCC among patients with cirrhosis. This …

Computed tomography for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease

T Nadarevic, V Giljaca, A Colli… - Cochrane database …, 2021 - cochranelibrary.com
Background Hepatocellular carcinoma occurs mostly in people with chronic liver disease
and ranks sixth in terms of global incidence of cancer, and fourth in terms of cancer deaths …

[HTML][HTML] Alpha-fetoprotein: Past, present, and future

YH Yeo, YT Lee, HR Tseng, Y Zhu, S You… - Hepatology …, 2024 - journals.lww.com
Alpha-fetoprotein (AFP) is a glycoprotein that plays an important role in immune regulation
with critical involvement in early human development and maintaining the immune balance …