Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section
E Christofi, P Barran - Chemical Reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …
MS) techniques has provided substantial insights into the field of structural biology over the …
Physicochemical stability of monoclonal antibodies: a review
Y Le Basle, P Chennell, N Tokhadze, A Astier… - Journal of …, 2020 - Elsevier
Monoclonal antibodies (mAbs) are subject to instability issues linked to their protein nature.
In this work, we review the different mechanisms that can be linked to monoclonal antibodies …
In this work, we review the different mechanisms that can be linked to monoclonal antibodies …
Evaluation of peptide/protein self-assembly and aggregation by spectroscopic methods
MF Pignataro, MG Herrera, VI Dodero - Molecules, 2020 - mdpi.com
The self-assembly of proteins is an essential process for a variety of cellular functions
including cell respiration, mobility and division. On the other hand, protein or peptide …
including cell respiration, mobility and division. On the other hand, protein or peptide …
Review of the current state of protein aggregation inhibition from a materials chemistry perspective: Special focus on polymeric materials
Protein instability caused by exposure to external additives or severe stress may result in
different diseases. Of these diseases, many are triggered by protein misfolding and …
different diseases. Of these diseases, many are triggered by protein misfolding and …
Mass spectrometry methods for measuring protein stability
DD Vallejo, C Rojas Ramírez, KF Parson, Y Han… - Chemical …, 2022 - ACS Publications
Mass spectrometry is a central technology in the life sciences, providing our most
comprehensive account of the molecular inventory of the cell. In parallel with developments …
comprehensive account of the molecular inventory of the cell. In parallel with developments …
Process analytical technologies and data analytics for the manufacture of monoclonal antibodies
MK Maruthamuthu, SR Rudge, AM Ardekani… - Trends in …, 2020 - cell.com
Process analytical technology (PAT) for the manufacture of monoclonal antibodies (mAbs) is
defined by an integrated set of advanced and automated methods that analyze the …
defined by an integrated set of advanced and automated methods that analyze the …
Phage-Displayed Nanobody as a Sensitive Nanoprobe to Enhance Chemiluminescent Immunoassay for Cronobacter sakazakii Detection in Dairy Products
Y Zhang, X Liao, G Yu, J Wei, P Wang… - Analytical …, 2023 - ACS Publications
The exploitation of stable, high-affinity, and low-cost nanoprobes is essential to develop
immunoassays for real-time monitoring of foodborne pathogens, so as to safeguard human …
immunoassays for real-time monitoring of foodborne pathogens, so as to safeguard human …
nanoDSF as screening tool for enzyme libraries and biotechnology development
AO Magnusson, A Szekrenyi, HJ Joosten… - The FEBS …, 2019 - Wiley Online Library
Enzymes are attractive tools for synthetic applications. To be viable for industrial use,
enzymes need sufficient stability towards the desired reaction conditions such as high …
enzymes need sufficient stability towards the desired reaction conditions such as high …
Ionic liquids and deep eutectic solvents for enhanced delivery of antibodies in the gastrointestinal tract
Monoclonal antibodies (mAbs) are currently used for the treatment of numerous conditions
including cancer, psoriasis, arthritis, and atopic dermatitis, among others. All mAbs are …
including cancer, psoriasis, arthritis, and atopic dermatitis, among others. All mAbs are …
Synthesis and Application of CeO2/SnS2 Heterostructures as a Highly Efficient Coreaction Accelerator in the Luminol–Dissolved O2 System for Ultrasensitive …
Electrocheluminescence (ECL) immunoassay amplified by coreaction accelerators has
experienced major breakthroughs in ultrasensitive detection of biomarkers. Herein …
experienced major breakthroughs in ultrasensitive detection of biomarkers. Herein …