Neurotrophin signaling is essential for normal nervous system development and adult
function. Neurotrophins are secreted proteins that signal via interacting with two …

The p75 neurotrophin receptor (p75 NTR) functions at the molecular nexus of cell death,
survival, and differentiation. In addition to its contribution to neurodegenerative diseases and …

The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral
nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here …

Axonal transport ensures long-range delivery of essential cargoes between proximal and
distal compartments, and is needed for neuronal development, function, and survival …

Objective: To evaluate urinary neurotrophin receptor p75 extracellular domain (p75ECD)
levels as disease progression and prognostic biomarkers in amyotrophic lateral sclerosis …

Neurodegenerative diseases are a group of nervous system conditions characterised
pathologically by the abnormal deposition of protein throughout the brain and spinal cord …

Aim We evaluated several sarcopenia‐related hormones, cytokines and uremic toxins to
identify the humoral factors associated with sarcopenia and frailty in Japanese hemodialysis …

Therapeutic monoclonal antibodies are mainly produced in mammalian cells to date.
However, unglycosylated antibody fragments can also be produced in the bacterium …

Tropomyosin receptor kinase B (TrkB) and its primary ligand brain-derived neurotrophic
factor (BDNF) are expressed in the neuromuscular system, where they affect neuronal …

Recent progress in the research for underlying mechanisms in neurodegenerative diseases,
including Alzheimer disease (AD), Parkinson disease (PD), and amyotrophic lateral …