Changes in cortical manifold structure following stroke and its relation to behavioral recovery in the male macaque

JY Nashed, DJ Gale, JP Gallivan, DJ Cook - Nature Communications, 2024 - nature.com
Stroke, a major cause of disability, disrupts brain function and motor skills. Previous
research has mainly focused on reorganization of the motor system post-stroke, but the …

Distinct patterns of cortical manifold expansion and contraction underlie human sensorimotor adaptation

DJ Gale, CN Areshenkoff… - Proceedings of the …, 2022 - National Acad Sciences
Sensorimotor learning is a dynamic, systems-level process that involves the combined
action of multiple neural systems distributed across the brain. Although much is known about …

Distinct manifold encoding of navigational information in the subiculum and hippocampus

S Nakai, T Kitanishi, K Mizuseki - Science Advances, 2024 - science.org
The subiculum (SUB) plays a crucial role in spatial navigation and encodes navigational
information differently from the hippocampal CA1 area. However, the representation of …

Cerebellar degeneration impairs strategy discovery but not strategy recall

JS Tsay, L Schuck, RB Ivry - The Cerebellum, 2023 - Springer
The cerebellum is recognized to play a critical role in the automatic and implicit process by
which movement errors are used to keep the sensorimotor system precisely calibrated …

Reconfigurations of cortical manifold structure during reward-based motor learning

Q Nick, DJ Gale, C Areshenkoff, A De Brouwer… - Elife, 2024 - elifesciences.org
Adaptive motor behavior depends on the coordinated activity of multiple neural systems
distributed across the brain. While the role of sensorimotor cortex in motor learning has been …

Distinct patterns of connectivity with the motor cortex reflect different components of sensorimotor learning

CN Areshenkoff, AJ de Brouwer, DJ Gale… - PLoS …, 2024 - journals.plos.org
Sensorimotor learning is supported by multiple competing processes that operate
concurrently, making it a challenge to elucidate their neural underpinnings. Here, using …

The structural-functional neural architectures of implicit and explicit motor learning

CN Areshenkoff, AJ de Brouwer, DJ Gale, JY Nashed… - bioRxiv, 2023 - biorxiv.org
The ability of the central nervous system to learn new mappings between motor commands
and sensory feedback is critical for adaptive behaviour. Substantial behavioral evidence …

The engagement of the cerebellum and basal ganglia enhances expertise in a sensorimotor adaptation task

JB Tan, E Müller, A Zahorodnii, JM Shine - Imaging Neuroscience, 2024 - direct.mit.edu
The ability to adapt to changes in the environment is essential for skilled performance,
especially in competitive sports and events, where experts consistently perform at the …

Visual statistical learning is associated with changes in low-dimensional cortical architecture

K Rowchan - 2024 - search.proquest.com
Our ability to automatically learn environmental regularities over time to make predictions
about the world is central to human cognition and behaviour. Despite its importance, the …

Individual variability in sensorimotor learning reflects trait-like neurobehavioral subject factors

CN Areshenkoff, AJ de Brouwer, D Standage… - bioRxiv, 2024 - biorxiv.org
Models of Human motor behaviour often emphasize the computations performed by the
motor system during learning. Yet, there is an emerging consensus that the learning of even …