CYP2D6 genotype is increasingly being integrated into practice to guide prescribing of
certain medications. The CYP2D6 drug metabolizing enzyme is susceptible to inhibition by …

Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …

Clinical decision support (CDS) is an essential part of any pharmacogenomics (PGx)
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …

Abstract Background Pharmacogenomics (PGx) can provide valuable pharmacokinetic and
pharmacodynamic information for the pharmacist's assessment of drug therapy, especially …

Introduction CYP2D6 contributes to the metabolism of approximately 20–25% of drugs.
However, CYP2D6 is highly polymorphic and different alleles can lead to impacts ranging …

The activity of cytochrome P450 enzymes is influenced by genetic and nongenetic factors;
hence, the metabolism of exogenous psychotropic medications and potentially some …

Pharmacogenetic testing (PGT) is increasingly being used as a tool to guide clinical
decisions. This article describes the development of an outpatient, pharmacist-led …

Several healthcare organizations have developed pre-emptive pharmacogenetic testing
programs, where testing is undertaken prior to the prescription of a medicine. This review …

Pharmacogenetic (PGx) literature has shown beneficial outcomes in safety, efficacy and cost
when evidence-based gene-drug decision making is incorporated into clinical practice. PGx …

Clinical implementation of pharmacogenomics (PGx) is slow. Previous studies have
identified some inconsistencies among clinical PGx recommendations, but the prevalence …