[HTML][HTML] Digital pathology and artificial intelligence in translational medicine and clinical practice

V Baxi, R Edwards, M Montalto, S Saha - Modern Pathology, 2022 - Elsevier
Traditional pathology approaches have played an integral role in the delivery of diagnosis,
semi-quantitative or qualitative assessment of protein expression, and classification of …

Total neoadjuvant therapy in rectal cancer: a systematic review and meta-analysis of treatment outcomes

F Petrelli, F Trevisan, M Cabiddu, G Sgroi… - Annals of …, 2020 - journals.lww.com
Background: The addition of induction chemotherapy to concomitant neoadjuvant
chemoradiation in locally advanced rectal cancer could increase pathological downstaging …

Neoadjuvant and adjuvant pembrolizumab in resectable locally advanced, human papillomavirus–unrelated head and neck cancer: a multicenter, phase II trial

R Uppaluri, KM Campbell, AM Egloff, P Zolkind… - Clinical Cancer …, 2020 - AACR
Purpose: Pembrolizumab improved survival in patients with recurrent or metastatic head and
neck squamous-cell carcinoma (HNSCC). The aims of this study were to determine if …

A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta …

F Dossa, TR Chesney, SA Acuna… - The lancet …, 2017 - thelancet.com
Background A watch-and-wait approach for patients with clinical complete response to
neoadjuvant chemoradiation could avoid the morbidity of conventional surgery for rectal …

Utility of ctDNA in predicting response to neoadjuvant chemoradiotherapy and prognosis assessment in locally advanced rectal cancer: A prospective cohort study

Y Wang, L Yang, H Bao, X Fan, F Xia, J Wan… - PLoS …, 2021 - journals.plos.org
Background For locally advanced rectal cancer (LARC) patients who receive neoadjuvant
chemoradiotherapy (nCRT), there are no reliable indicators to accurately predict …

Updates of risk factors for anastomotic leakage after colorectal surgery

EC Zarnescu, NO Zarnescu, R Costea - Diagnostics, 2021 - mdpi.com
Anastomotic leakage is a potentially severe complication occurring after colorectal surgery
and can lead to increased morbidity and mortality, permanent stoma formation, and cancer …

Oncological and survival outcomes in watch and wait patients with a clinical complete response after neoadjuvant chemoradiotherapy for rectal cancer: a systematic …

M Dattani, RJ Heald, G Goussous, J Broadhurst… - Annals of …, 2018 - journals.lww.com
Objective: The aim of this study was to evaluate the oncological and survival outcomes of a
Watch and Wait policy in rectal cancer after a clinical complete response (cCR) following …

[HTML][HTML] EURECCA colorectal: multidisciplinary management: European consensus conference colon & rectum

CJH van de Velde, PG Boelens, JM Borras… - European journal of …, 2014 - Elsevier
Background Care for patients with colon and rectal cancer has improved in the last 20 years;
however considerable variation still exists in cancer management and outcome between …

Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy

JD Smith, JA Ruby, KA Goodman, LB Saltz… - Annals of …, 2012 - journals.lww.com
Methods: Patients completing neoadjuvant chemoradiotherapy (CRT) for stage I to III rectal
cancer between January 2006 and August 2010 were retrospectively reviewed. Median …

Increasing the interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer: a meta-analysis of published studies

F Petrelli, G Sgroi, E Sarti, S Barni - Annals of surgery, 2016 - journals.lww.com
Objective: The aim of this meta-analysis was to demonstrate whether a longer interval
between the end of neoadjuvant chemoradiotherapy (CRT) and surgery is associated with a …