Computational methods for discovering gene networks from expression data

WP Lee, WS Tzou - Briefings in bioinformatics, 2009 - academic.oup.com
Designing and conducting experiments are routine practices for modern biologists. The real
challenge, especially in the post-genome era, usually comes not from acquiring data, but …

Mechanisms and evolution of control logic in prokaryotic transcriptional regulation

SAFT van Hijum, MH Medema… - … and Molecular Biology …, 2009 - Am Soc Microbiol
SUMMARY A major part of organismal complexity and versatility of prokaryotes resides in
their ability to fine-tune gene expression to adequately respond to internal and external …

Turbulent geodynamo simulations: a leap towards Earth's core

N Schaeffer, D Jault, HC Nataf… - Geophysical Journal …, 2017 - academic.oup.com
We present an attempt to reach realistic turbulent regime in direct numerical simulations of
the geodynamo. We rely on a sequence of three convection-driven simulations in a rapidly …

Magnetic activity in the HARPS M dwarf sample-The rotation-activity relationship for very low-mass stars through R'HK

N Astudillo-Defru, X Delfosse, X Bonfils… - Astronomy & …, 2017 - aanda.org
Context. Atmospheric magnetic fields in stars with convective envelopes heat stellar
chromospheres, and thus increase the observed flux in the Ca ii H and K doublet. Starting …

Powering stellar magnetism: energy transfers in cyclic dynamos of Sun-like stars

AS Brun, A Strugarek, Q Noraz, B Perri… - The Astrophysical …, 2022 - iopscience.iop.org
We use the anelastic spherical harmonic code to model the convective dynamo of solar-type
stars. Based on a series of 15 3D MHD simulations spanning four bins in rotation and mass …

[图书][B] Biomolecular networks: methods and applications in systems biology

AY Zomaya, Y Pan - 2009 - books.google.com
Alternative techniques and tools for analyzing biomolecular networks With the recent rapid
advances in molecular biology, high-throughput experimental methods have resulted in …

Explaining the coexistence of large-scale and small-scale magnetic fields in fully convective stars

RK Yadav, UR Christensen, J Morin… - The Astrophysical …, 2015 - iopscience.iop.org
Despite the lack of a shear-rich tachocline region, low-mass fully convective (FC) stars are
capable of generating strong magnetic fields, indicating that a dynamo mechanism …

The underexplored frontier of ice giant dynamos

KM Soderlund, S Stanley - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
The Voyager 2 flybys of Uranus and Neptune revealed the first multipolar planetary
magnetic fields and highlighted how much we have yet to learn about ice giant planets. In …

A closer look at cross-validation for assessing the accuracy of gene regulatory networks and models

S Tabe-Bordbar, A Emad, SD Zhao, S Sinha - Scientific reports, 2018 - nature.com
Cross-validation (CV) is a technique to assess the generalizability of a model to unseen
data. This technique relies on assumptions that may not be satisfied when studying …

The solar-stellar connection

AS Brun, RA García, G Houdek, D Nandy… - Space Science …, 2015 - Springer
We discuss how recent advances in observations, theory and numerical simulations have
allowed the stellar community to progress in its understanding of stellar convection, rotation …